3-Hydroxypropionitrile CAS 109-78-4 Purity >98.0% (GC)

Short Description:

Chemical Name: 3-Hydroxypropionitrile

Synonyms: Ethylene Cyanohydrin 

CAS: 109-78-4

Purity: >98.0% (GC)

Appearance: Colorless Clear Liquid 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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109-78-4 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 3-Hydroxypropionitrile (Ethylene Cyanohydrin) (CAS: 109-78-4) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Please contact: alvin@ruifuchem.com

109-78-4 - Chemical Properties:

Chemical Name 3-Hydroxypropionitrile 
Synonyms Ethylene Cyanohydrin; 2-Cyanoethanol; Hydracrylonitrile; 3-Hydroxypropanenitrile; beta-HPN; beta-Cyanoethanol; beta-Hydroxypropionitrile; 2-Cyanoethyl Alcohol; 2-Hydroxycyanoethane
Stock Status In Stock, Commercial Production  
CAS Number 109-78-4
Molecular Formula C3H5NO
Molecular Weight 71.08 g/mol
Melting Point -46℃(lit.) 
Boiling Point 227.0~228.0℃(lit.) 
Flash Point 128℃(262°F)  
Density 1.04 g/mL at 25℃(lit.) 
Refractive Index n20/D 1.425(lit.)
Store Under Inert Gas Store Under Inert Gas
Sensitive Light Sensitive, Air Sensitive 
Solubility  Completely Miscible in Water. Miscible with Acetone, Alcohol 
COA & MSDS Available
Place of Origin  Shanghai, China
Brand Ruifu Chemical

109-78-4 - Specifications:

Items Specifications  Results
Appearance Colorless Clear Liquid   Colorless Clear Liquid  
Water by Karl Fischer  <0.50% 0.18% 
Density (20℃)  1.045~1.049 Conforms 
Refractive Index n20/D 1.4245~1.4285 Conforms 
3-Hydroxypropionitrile Purity >98.0% (GC)  99.28% 
Infrared Spectrum Consistent with Structure Complies 
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications

109-78-4 - Stability:

Stable. Flammable. Incompatible with strong oxidizing agents. Reacts with water or steam to release toxic vapours. Reacts violently with acids, amines, inorganic bases. Corrodes mild steel.

Package/Storage/Shipping:

Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Incompatible with oxidizing agents.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

109-78-4 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S24/25 - Avoid contact with skin and eyes.
UN IDs 2810
WGK Germany 1
RTECS MU5250000
FLUKA BRAND F CODES 8-10
TSCA Yes
HS Code 2926 9090.90
Hazard Note Irritant

109-78-4 - Application:

3-Hydroxypropionitrile (Ethylene Cyanohydrin) (CAS: 109-78-4) is used as pharmaceutical, organic synthesis intermediates.
3-Hydroxypropionitrile is an aliphatic nitrile to which a hydroxyl group is attached at the ?-carbon. The nitrogen atom contains a lone pair of electrons, which is largely responsible for the polarization of the C≡N triple bond. Because of the greater electronegativity of nitrogen compared to carbon, nucleophilic compounds can attack the electrophilic carbon atom (Schaefer 1970), although the nitrogen atom is an excellent donor site for complexing with Lewis acids (Sheppard 1970). The hydroxyl functional group on the other end of the molecule is also polar; like the nitrile nitrogen, its oxygen is basic and nucleophilic. Reactions of the -OH group can involve the breaking of either of two bonds: the C-OH bond, with removal of the -OH group; or the O-H bond, with removal of -H. Either kind of reaction can involve substitution, in which a group replaces the -H or -OH, or elimination, in which a double bond is formed (Morrison and Boyd 1973).
3-Hydroxypropionitrile has been used as polar solvent to investigate the orientation of the phospholipid at the surface of the polar solvents by neutral impact collision ion scattering spectroscopy and as a reagent for carboxyl protection in peptide synthesis. It has been used also in solid state composite electrolyte for dye-sensitized solar cells.

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