2-Bromo-4′-Cyanoacetophenone CAS 20099-89-2 Purity >98.0% (HPLC)

Short Description:

Chemical Name: 2-Bromo-4′-Cyanoacetophenone

4-(2-Bromoacetyl)benzonitrile; 4-Cyanophenacyl Bromide

CAS: 20099-89-2

Purity: >98.0% (HPLC) 

Appearance: Off-White to Light Yellow / Pinkish Crystals 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 2-Bromo-4′-Cyanoacetophenone (CAS: 20099-89-2) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name 2-Bromo-4′-Cyanoacetophenone 
Synonyms 4-(2-Bromoacetyl)benzonitrile; 4-Cyanophenacyl Bromide; 4-(Bromoacetyl)benzonitrile; 4-(2-Bromo-Acetyl)-Benzonitrile; ω-Bromo-4-Cyanoacetophenone; p-Bromoacetylbenzonitrile 
CAS Number 20099-89-2 
CAT Number RF2929
Stock Status In Stock, Production Capacity 20 Tons per Month    
Molecular Formula C9H6BrNO 
Molecular Weight 224.06  
Melting Point 92.0 to 96.0℃(lit.)
Boiling Point 342.4±22.0℃
Density 1.56±0.10 g/cm3
Solubility  Soluble in Methanol
Hazard Note  Corrosive
Hazard Class  6.1 (8); Poison, Corrosive
Packing Group  II
HS Code  29269090
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Off-White to Light Yellow / Pinkish Crystals
Purity / Analysis Method >98.0% (HPLC) 
Melting Point 92.0 to 96.0℃
Water (by Karl Fischer) <0.50%
Single Impurity 1 <1.00%
Single Impurity 2 <0.50%
Single Impurity 3 <0.50%
Total Impurities <2.00%
1 H NMR Spectrum Consistent With Structure
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates; Isavuconazole Impurity / Intermediate

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

2-Bromo-4′-Cyanoacetophenone, also known as 4-(2-Bromoacetyl)benzonitrile; 4-Cyanophenacyl Bromide, (CAS: 20099-89-2) is used as raw materials for organic synthesis and pharmaceutical intermediates, etc. 2-Bromo-4′-Cyanoacetophenone is an intermediate and impurity of Isavuconazole (CAS: 241479-67-4). Isavuconazole is a new triazole currently undergoing phase III clinical trials. This compound has shown in vitro activity against a large number of clinical important yeasts and molds including Aspergillus spp., Fusarium spp., Scedosporium spp., Candida spp., the Zygomycetes and Cryptococcus spp. Isavuconazole is produced and developed by Basilea Pharmaceutica and, in common with the other azoles, works by inhibition of ergosterol synthesis. Isavuconazole is a water-soluble compound (the only broad-spectrum water soluble triazole) with oral and intravenous formulations and excellent bioavailability.  Its long elimination half-life allows up to once-weekly dosing. It is an antifungal drug used for the treatment of invasive aspergillosis and invasive mucormycosis.

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