(R)-(-)-3-Carbamoymethyl-5-Methylhexanoic Acid CAS 181289-33-8 Purity >99.0% (HPLC) Pregabalin Intermediate Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (R)-(-)-3-Carbamoymethyl-5-Methylhexanoic Acid (CAS: 181289-33-8) with high quality, commercial production, intermediate of Pregabalin (CAS: 148553-50-8). Ruifu Chemical can provide worldwide delivery, small and bulk quantities available, strong after-sale service. Welcome to order. Please contact: alvin@ruifuchem.com
| Chemical Name | (R)-(-)-3-Carbamoymethyl-5-Methylhexanoic Acid |
| Synonyms | (R)-3-(2-Amino-2-Oxoethyl)-5-Methylhexanoic Acid; RCMH; Pregabalin Impurity III |
| CAS Number | 181289-33-8 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C9H17NO3 |
| Molecular Weight | 187.24 |
| Melting Point | 126.0~133.0℃ |
| Density | 1.080±0.06 g/cm3 |
| COA & MSDS | Available |
| Place of Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Characteristics | White or Off-White Crystalline Powder | Conforms |
| Assay (Titration) | More than 99.0% | 99.55% |
| Identification | IR & HPLC | Conforms |
| Purity / Analysis Method | More than 99.0% (HPLC) | 99.71% |
| Melting Point | 126.0~133.0℃ | 129.1~131.5℃ |
| S-Isomer | Less than 1.00% | 0.28% |
| A-Phenylethylamine | Less than 0.50% | Conforms |
| Dicarboxylic Acid | Less than 0.30% | Conforms |
| Any Single Impurity | Less than 0.50% | Conforms |
| Loss on Drying | Less than 1.00% | 0.38% |
| Residue on Ignition | Less than 0.30% | 0.022% |
| Test Standard | Enterprise Standard | Conforms |
| Usage | Intermediate of Pregabalin (CAS: 148553-50-8) | |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
(R)-(-)-3-Carbamoymethyl-5-Methylhexanoic Acid (CAS: 181289-33-8) is a useful chemical intermediate for manufacturing of the anticonvulsant drug, Pregabalin (CAS: 148553-50-8). Pregabalin is a new antiepileptic drug, having a γ-amino butyric acid structure on its molecular structure, which has anticonvulsant effects, and is successfully developed by the company Pfizer for the treatment of peripheral neuropathic pain, or adjuvant treatment of partial seizures. Pregabalin is a second- generation antiepileptic drug (AED) known with the proprietary brand name of Lyrica (Pfizer, Tadworth) in the UK and USA (Pfizer, New York, NY).
