1-Boc-Pyrrolidine-3-Carboxylic Acid CAS 59378-75-5 Purity >98.0% (HPLC)

Short Description:

1-Boc-Pyrrolidine-3-Carboxylic Acid

Synonyms: 1-Boc-3-Pyrrolidinecarboxylic Acid

CAS: 59378-75-5

Purity: >98.0% (HPLC)

Appearance: White or Light-Yellow Solid

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 1-Boc-Pyrrolidine-3-Carboxylic Acid (CAS: 59378-75-5) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase 1-Boc-Pyrrolidine-3-Carboxylic Acid, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name 1-Boc-Pyrrolidine-3-Carboxylic Acid 
Synonyms N-Boc-Pyrrolidine-3-Carboxylic Acid; 1-Boc-3-Pyrrolidinecarboxylic Acid; 3-Carboxy-1-Boc-Pyrrolidine; 1-(tert-Butoxycarbonyl)-3-Pyrrolidinecarboxylic Acid; 1-(tert-Butoxycarbonyl)pyrrolidine-3-Carboxylic Acid; N-(tert-Butoxycarbonyl)pyrrolidine-3-carboxylic Acid; Pyrrolidine-1,3-Dicarboxylic Acid 1-tert-Butyl Ester; N-Boc-β-Proline; 1-N-Boc-beta-Proline
Stock Status In Stock 
CAS Number 59378-75-5
Molecular Formula C10H17NO4
Molecular Weight 215.25 g/mol
Melting Point 133.0 to 139.0℃ 
Density 1.20±0.06 g/cm3 
Sensitive Heat Sensitive 
Solubility  Soluble in Chloroform
Storage Temp.  Cool & Dry Place (2~8℃) 
COA & MSDS Available
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance White or Light-Yellow Solid White Solid 
Melting Point 133.0 to 139.0℃ 137.0~138.0℃
Water by Karl Fischer  <0.50% 0.10%
Purity / Analysis Method >98.0% (HPLC)  98.1% 
Infrared Spectrum Conforms to Structure Complies      
1H NMR Spectrum  Conforms to Structure Complies      
Conclusion The product has been tested & complies with the given specifications

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

59378-75-5 - Risk and Safety:

Risk Codes
R36/37/38 - Irritating to eyes, respiratory system and skin.
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R41 - Risk of serious damage to eyes
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
S60 - This material and its container must be disposed of as hazardous waste.
S39 - Wear eye / face protection.
UN IDs UN 3077 9/PG 3
WGK Germany 3
HS Code 2933990099
Hazard Class IRRITANT
Packing Group Ⅲ 

Application:

1-Boc-Pyrrolidine-3-Carboxylic Acid (CAS: 59378-75-5) is a pyrrole carboxylic acid compound, as an important intermediate of fine chemicals, it is widely used in the fields of medicine, food, pesticide, daily chemicals and so on.
1-Boc-Pyrrolidine-3-Carboxylic Acid is a reactant used in the synthesis of potent and highly selective ERK1,2 inhibitors. 

Synthesis Method:

With Pyrrolidine-3-Carboxylic Acid as raw material, the target compound, 1-Boc-Pyrrolidin-3-Carboxylic Acid, was prepared by reaction with di-tert-Butyl Dicarbonate under the condition of Et 3 N/MeOH for Boc protection. The reaction formula for preparation of 1-Boc-Pyrrolidin-3-Carboxylic Acid.

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