Xylazine Hydrochloride CAS 23076-35-9 Assay 98.0%-102.0% High Purity

Short Description:

Chemical Name: Xylazine Hydrochloride 

CAS HCl: 23076-35-9

CAS Free Base: 7361-61-7

Assay: 98.0%-102.0% (HPLC)

Appearance: White to Almost White Crystalline Powder

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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23076-35-9 - Description:

Ruifu Chemical is the leading manufacturer of Xylazine Hydrochloride (CAS: 23076-35-9)Xylazine (CAS: 7361-61-7) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Xylazine Hydrochloride or Xylazine, please contact us by e-mail: alvin@ruifuchem.com

23076-35-9 - Chemical Properties:

Chemical Name Xylazine Hydrochloride
Synonyms Xylazine HCl; BAY 1470 Hydrochloride; 2-(2,6-Dimethylphenylamino)-5,6-Dihydro-4H-Thiazine Hydrochloride, 5,6-Dihydro-2-(2,6-Xylidino)-4H-1,3-Thiazine Hydrochloride; BAY-Va 1470; Celactal; Narcosyl
Stock Status In Stock, Commercial Production  
CAS HCl   23076-35-9
CAS Free Base 7361-61-7
Molecular Formula C12H16N2S·HCl
Molecular Weight 256.80 g/mol
Melting Point 164.0-168.0℃ 
Water Solubility  Soluble in Water, Almost Transparency
Storage Temperature Store Long-Term at 2-8℃
COA & MSDS Available
Product Categories Veterinary Medicine Sedative
Origin of Product    Shanghai, China
Brand Ruifu Chemical

23076-35-9 - Specifications:

Items Specifications  Results
Appearance White to Almost White Crystalline Powder  White Crystalline Powder
Identification A: Infrared Absorption   Complies
Identification B:  Thin-Layer Chromatographic Identification Test Complies
Melting Point 164.0-168.0℃ 164.0-165.0℃
pH 4.0-6.0 5.2
Loss on Drying ≤1.00% (105℃ for 4 hours) 0.27%
Residue on Ignition ≤0.10% 0.06%
Heavy Metals (Pb) ≤20ppm <10ppm 
Chromatographic Purity Should be Match with the Standard Complies
Assay / Analysis Method 98.0%-102.0%  99.63%
Conclusion The product has been tested and complies with the given specifications

23076-35-9 - Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2-8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery. 

23076-35-9 - USP35 Standard:

Xylazine Hydrochloride
C12H16N2S·HCl 256.80
4H-1,3-Thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-, monohydrochloride.
5,6-Dihydro-2-(2,6-xylidino)-4H-1,3-thiazine hydrochloride [23076-35-9].
» Xylazine Hydrochloride contains not less than 98.0 percent and not more than 102.0 percent of C12H16N2S·HCl.
Packaging and storage- Preserve in tight containers. Store at 25, excursions permitted between 15 and 30.
Labeling- Where it is intended for veterinary use only, the label so states.
USP Reference standards <11>-
USP Xylazine Hydrochloride RS
A: Infrared Absorption<197K>.
B: Thin-Layer Chromatographic Identification Test <201>-
Test solution: 5 mg per mL, in methanol.
Developing solvent system: methanol and ammonium hydroxide (98.5:1.5).
Procedure- Separately apply 1 µL of the Test solution and the Standard solution. Allow the applications to dry with the aid of a stream of nitrogen, develop in a saturated chromatographic chamber, and dry the plate in a current of air: the size, intensity, and RF value of the principal spot obtained from the Test solution correspond to those of the principal spot obtained from the Standard solution.
Melting range <741>: between 164 and 168.
pH <791>: between 4.0 and 6.0, in a solution (1 in 100).
Loss on drying <731>- Dry it at 105 for 4 hours: it loses not more than 1.0% of its weight.
Residue on ignition <281>: not more than 0.1%.
Heavy metals, Method II <231>: 20 µg per g.
Chromatographic purity- Examine the chromatogram obtained from the Assay preparation. Calculate the percentage of impurities in the Xylazine Hydrochloride taken by the formula:
100rs / (rU + rs)
in which rs is the sum of the areas of all the impurity peaks observed; and rU is the area of the xylazine peak: the sum of the impurity responses is not greater than 2.0%.
Mobile phase- Dissolve 6.0 g of sodium 1-heptanesulfonate in 2500 mL of water, add 60 mL of glacial acetic acid, dilute with water to 3000 mL, and mix. Prepare a mixture of 2200 mL of this solution and 1800 mL of methanol, and pass through a filter having a 0.5-µm or finer porosity. Make adjustments if necessary (see System Suitability under Chromatography <621>).
Standard preparation- Prepare a solution of USP Xylazine Hydrochloride RS in Mobile phase having a known concentration of about 1 mg per mL.
Assay preparation- Transfer about 25 mg of Xylazine Hydrochloride, accurately weighed, to a 25-mL volumetric flask, dissolve in and dilute with Mobile phase to volume, and mix.
Chromatographic system (see Chromatography <621>)- The liquid chromatograph is equipped with a 254-nm detector, a 2-mm × 2-cm guard column that contains packing L1, and a 3.9-mm × 30-cm analytical column that contains packing L1 and is maintained at a constant temperature of about 40. The flow rate is about 2.5 mL per minute. Chromatograph the Standard preparation, and record the peak responses as directed for Procedure: the relative standard deviation for replicate injections is not more than 2.0%. [note-After daily use, rinse the column with 100 mL of acetonitrile and with 100 mL of methanol, and store the column containing methanol.]
Procedure- Separately inject equal volumes (about 20 µL) of the Standard preparation and the Assay preparation into the chromatograph, record the chromatograms, and measure the responses for the major peaks. Calculate the quantity, in mg, of C12H16N2S·HCl in the portion of Xylazine Hydrochloride taken by the formula:
25C(rU / rS)
in which C is the concentration, in mg per mL, of USP Xylazine Hydrochloride RS in the Standard preparation; and rU and rS are the areas of the xylazine peak responses in the chromatograms obtained from the Assay preparation and the Standard preparation, respectively.

23076-35-9 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

23076-35-9 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

23076-35-9 - Risk and Safety:

Hazard Symbols T - Toxic
Risk Codes
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs 2811
HS Code 2942000000

23076-35-9 - Application:

Xylazine Hydrochloride (CAS: 23076-35-9) is the hydrochloride salt of xylazine. It is used as a sedative, analgesic, and muscle relaxant in veterinary medicine. It has a role as an alpha-adrenergic agonist, an analgesic, an emetic, a muscle relaxant and a sedative. Xylazine Hydrochloride is a common veterinary drug used for sedation, anesthesia, muscle relaxation and analgesia in animals such as horses, cattle and other mammals.

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