tert-Butyl L-Pyroglutamate CAS 35418-16-7 (H-Pyr-OtBu) Assay >98.5% (TLC)

Short Description:

Chemical Name: tert-Butyl L-Pyroglutamate

H-Pyr-OtBu; L-Pyroglutamic Acid tert-Butyl Ester 

CAS: 35418-16-7  

Assay: >98.5% (TLC) 

Appearance: White or Off-White Crystalline Powder 

Amino Acids & Derivatives, High Quality 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of tert-Butyl L-Pyroglutamate (H-Pyr-OtBu) (CAS: 35418-16-7) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. If you need tert-Butyl L-Pyroglutamate, Please contact: alvin@ruifuchem.com 

Chemical Properties:

Chemical Name tert-Butyl L-Pyroglutamate 
Synonyms H-Pyr-OtBu; L-Pyr-OtBu; L-Pyroglutamic Acid tert-Butyl Ester; tert-Butyl (S)-5-Oxopyrrolidine-2-Carboxylate; tert-Butyl 5-oxo-L-Prolinate; tert-Butyl (S)-2-Pyrrolidone-5-Carboxylate; (S)-2-Pyrrolidone-5-Carboxylic Acid t-Butyl Ester; tert-Butyl (S)-5-oxo-2-Pyrrolidinecarboxylate; (S)-5-Oxopyrrolidine-2-Carboxylic Acid tert-Butyl Ester
Stock Status In Stock, Production Capacity To Tons  
CAS Number 35418-16-7 
Molecular Formula C9H15NO3
Molecular Weight 185.22  
Melting Point 90.0~95.0℃
Density 1.099±0.06 g/cm3 
Solubility  Soluble in Methanol
Storage Temp.  Sealed in Dry, Store at Room Temperature
Shipping Normal
COA & MSDS Available
Classification Amino Acids & Derivatives 
Brand Ruifu Chemical

Safety Information:

Hazard Codes Xi - Irritant  
Risk Statements 36/38 - Irritating to eyes and skin.  
Safety Statements 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany  
HS Code 2922491990          

Specifications:

Items Inspection Standards Results
Appearance White or Off-White Crystalline Powder Conforms          
Identification Infrared Absorption Spectrum Conforms
Specific Rotation [α]20/D +7.5° to +9.5° (C=1, MeOH)
+8.3°
Melting Point 90.0~95.0℃  Conforms          
Heavy Metals (as Pb) <20ppm <20ppm 
Loss on Drying <0.50% 0.28%
Assay / Analysis Method  >98.5% (TLC)    98.84% 
Infrared Spectrum Conforms to Structure Conforms          
Proton NMR Spectrum  Conforms to Structure Conforms          
Conclusion This Product by Inspection Accords with the Enterprise Standard
Main Uses Amino Acids and Derivatives; Pharmaceutical Intermediates

Package & Storage:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from light and moisture.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

tert-Butyl L-Pyroglutamate (H-Pyr-OtBu) (CAS: 35418-16-7) can be used as pharmaceutical intermediates.
Can be used:
As a starting material/synthon in the synthesis of angiotensin-converting enzyme inhibitors.
In the synthesis of phenanthroindolizidine alkaloids named (+)-tylophorine and antofine.
As a starting material in the synthesis of radioligands [18F]IUR-1602 and [18F]IUR-1601, applicable for imaging of P2X7R, a therapeutic target for neuroinflammation.

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