Terbinafine Hydrochloride CAS 78628-80-5 Purity >99.0% (T) (HPLC)
Leading Manufacturer and Supplier
Intermediates of Terbinafine Hydrochloride
Terbinafine Hydrochloride CAS 78628-80-5
N-Methyl-1-Naphthylmethylamine CAS 14489-75-9
3,3-Dimethyl-1-Butyne CAS 917-92-0
trans-1,3-Dichloropropene CAS 10061-02-6
Please contact: alvin@ruifuchem.com
| Chemical Name | Terbinafine Hydrochloride |
| Synonyms | Terbinafine HCl; trans-N-(6,6-Dimethyl-2-Hepten-4-ynyl)-N-Methyl-1-Naphthylmethylamine Hydrochloride; (E)-N,6,6-Trimethyl-N-(Naphthalen-1-ylmethyl)hept-2-en-4-yn-1-Amine Hydrochloride |
| CAS Number | 78628-80-5 |
| CAT Number | RF2719 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C21H25N·HCl |
| Molecular Weight | 327.90 |
| Melting Point | 204.0~208.0℃ |
| Sensitive | Hygroscopic. Light Sensitive, Air Sensitive, Heat Sensitive |
| Water Solubility | Slightly Soluble in Water |
| Solubility in Water | Soluble in Anhydrous Ethanol and Methanol, Almost Transparency |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White or Similar White Powder |
| Identification | Infrared Absorption Spectrophotometry. Comparison: Terbinafine Hydrochloride CRS |
| It Gives Reaction of Chlorides Using Anhydrous Ethanol R as Solvent | |
| Purity / Analysis Method | >99.0% (Nonaqueous Titration) |
| Purity / Analysis Method | >99.0% (HPLC) |
| Melting Point | 204.0~208.0℃ |
| Loss on Drying | <0.50% |
| Residue on Ignition | <0.20% |
| Heavy Metals | <20ppm |
| Single Impurity | <0.20% |
| Total Impurities | <0.50% |
| pH | 3.0~4.5 |
| Residual Solvents | |
| Ethy Acetate | <0.50% |
| Dichloromethan | <0.06% |
| Isopropanol | <0.50% |
| Infrared Spectrum | Conforms to Structure |
| Test Standard | Enterprise Standard |
Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Terbinafine Hydrochloride (CAS: 78628-80-5) is an oral antifungal agent for the treatment of Trichophyton (Red Trichophyton, Trichophyton rubrum, Trichophyton rubrum, Trichophyton rubrum and Trichophyton rubrum) Infection of skin, hair and nails caused by Microsporum canis and Fusarium oxysporum. It can also treat various rickets (body lice, tinea, hand, foot and head lice, etc.) as well as skin yeast infections caused by Candida (Candida albicans, etc.), and hyperthyroidism caused by mold (for fungal infections). 1. Terbinafine is mainly effective on the dermatophyte group of fungi. 2. As a 1% cream or powder, it is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream works in about half the time required by other antifungals. 3. Oral 250-mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests. Alternatives to oral administration have been studied. 4. Terbinafine may induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy. Terbinafine Hydrochloride entered the the first batch of country announced OTC directory in 2000. This product belongs to antifungal drugs. It has strong effect on shallow fungal infection, and can cure most of the fungal skin diseases through external use.
