MeOSuc-AAPV-pNA CAS 70967-90-7 Assay >98.0% (HPLC) Peptide Substrate

Short Description:

Peptide Sequence: MeOSuc-AAPV-pNA

Synonyms: MeOSuc-Ala-Ala-Pro-Val-pNA

CAS: 70967-90-7 

Assay: >98.0% (HPLC)  

Appearance: White or Off-White Crystalline Powder 

Highly Sensitive Peptide Substrate, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading supplier of MeOSuc-AAPV-pNA (CAS: 70967-90-7) with high quality. We can provide worldwide delivery, small and bulk quantities available. If you need MeOSuc-AAPV-pNA, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name MeOSuc-AAPV-pNA 
Synonyms MeOSuc-Ala-Ala-Pro-Val-pNA; N-Methoxysuccinyl-Ala-Ala-Pro-Val p-Nitroanilide; N-Methoxysuccinyl-Ala-Ala-Pro-Val-pNA; N-(Methoxysuccinyl)-L-Alanyl-L-Alanyl-L-Prolyl-L-Valine 4-Nitroanilide, N-(Methoxysuccinyl)-Ala-Ala-Pro-Val 4-Nitroanilide
Stock Status In Stock 
CAS Number 70967-90-7 
Molecular Formula C27H38N6O9
Molecular Weight 590.63 g/mol 
Melting Point 203.0~205.0℃ 
Boiling Point 958.4±65.0℃
Density 1.297±0.06 g/cm3 
COA & MSDS Available
Brand Ruifu Chemical

Safety Information:

Safety Statements 22-24/25           F    10-21  
WGK Germany HS Code           2922491990                        

Specifications:

Items Inspection Standards Results
Appearance White or Off-White Crystalline Powder Conforms          
Assay >98.0% 98.93%
Conclusion This Product by Inspection Accords with the Enterprise Standard
Main Uses Chromogenic Substrate  

Package & Storage:

PackagePenicillin Bottle, Aluminium foil bag, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from light and moisture.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

MeOSuc-AAPV-pNA (CAS: 70967-90-7) is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. MeOSuc-AAPV-pNA is cleaved at 405-410 nm. MeOSuc-AAPV-pNA, Chromogenic Substrate is a sensitive chromogenic substrate for PR3 (proteinase 3; PRTN3) and neutrophil elastase. PR3 is a polymorphonuclear leukocyte (PMNL) serine proteinase that degrades a variety of matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV and contributes to the proteolytic generation of antimicrobial peptides. Neutrophil elastase is a serine proteinase that during inflammation, is secreted by neutrophils to destroy bacteria as well as host tissue. Evaluating human and murine PR3 and neutrophil elastase enzymes are helpful to understanding PR3-related and inflammatory autoimmune processes. Researchers have used this product in cystic fibrosis research, as elastin degradation has been reported to increase in cystic fibrosis patients. Hydrolysis or cleavage of this substrate product can be detected at 405-410 nm. This product is not a suitable substrate for cathepsin G nor chymotrypsin.

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