Meldrum’s Acid CAS 2033-24-1 Purity >99.0% (HPLC) Meropenem Intermediate

Short Description:

Chemical Name: Meldrum’s Acid

Synonyms: 2,2-Dimethyl-1,3-Dioxane-4,6-Dione

CAS: 2033-24-1

Purity: >99.0% (HPLC)

Appearance: White to Off-White Crystalline Powder

Intermediate of Meropenem Series, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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2033-24-1 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Meldrum's Acid (2,2-Dimethyl-1,3-Dioxane-4,6-Dione) (CAS: 2033-24-1) with high quality, intermediate of Meropenem series. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Meldrum's Acid, Please contact: alvin@ruifuchem.com

2033-24-1 - Chemical Properties:

Chemical Name Meldrum's Acid  
Synonyms 2,2-Dimethyl-1,3-Dioxane-4,6-Dione; cycl-Isopropylidene Malonate; Malonic Acid Cyclic Isopropylidene Ester; Isopropylidene Malonate
Stock Status In Stock, Commercial Production  
CAS Number 2033-24-1
Molecular Formula C6H8O4
Molecular Weight 144.13 g/mol
Melting Point 93.0~97.0℃ 
Sensitive Heat Sensitive 
Solubility  Soluble in Methanol, Almost Transparency
COA & MSDS Available
Place of Origin  Shanghai, China
Shelf Life 2 Years When Properly Stored 
Brand Ruifu Chemical

2033-24-1 - Specifications:

Items Specifications  Results
Appearance White to Off-White Crystalline Powder White Crystalline Powder
Melting Point 93.0~97.0℃ 93.8~94.9℃
Water by Karl Fischer  <0.30% 0.10%
Single Impurity <0.50% Conforms 
Total Impurities <1.00% Conforms 
Meldrum's Acid Purity  >99.0% (HPLC)  99.74%
Infrared Spectrometry Conforms to Structure Conforms 
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Meropenem Series

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

2033-24-1 - Risk and Safety:

Risk Codes R36/37/38 - Irritating to eyes, respiratory system and skin.
R45 - May cause cancer
Safety Description S37/39 - Wear suitable gloves and eye/face protection
S24/25 - Avoid contact with skin and eyes.
S53 - Avoid exposure - obtain special instructions before use.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
RTECS JH0800000
FLUKA BRAND F CODES 10-21
TSCA Yes
Hazard Class IRRITANT

2033-24-1 - Application:

Meldrum's Acid (2,2-Dimethyl-1,3-Dioxane-4,6-Dione) (CAS: 2033-24-1), used as a pharmaceutical intermediate, intermediate of Meropenem series. Meropenem is another kind of parenteral administrated semi-synthetic carbapenem antibiotics after imipenem-cilastatin has entered into market in the United State. It can inhibit the bacterial cell wall synthesis through binding with the penicillin-binding proteins involved in cell wall synthesis (PBPs) through its covalent bond, thus playing its antibacterial effect.
Meldrum's Acid serves as an intermediate in a variety of organic synthesis reactions. It is commonly used as an alternative to acyclic malonic esters and generally acts as a C3O2 synthon in organic synthesis.  

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