Lithium Bis(trimethylsilyl)amide (LiHMDS) CAS 4039-32-1 (1 M in Toluene)

Short Description:

Lithium Bis(trimethylsilyl)amide, 1 M in Toluene

Synonyms: LiHMDS; LHMDS

CAS: 4039-32-1

Appearance: Yellow to Brown Liquid

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

4039-32-1 - Description:

Ruifu Chemical is the leading manufacturer of Lithium Bis(trimethylsilyl)amide (LiHMDS) (1 M in Toluene) (CAS: 4039-32-1) with high quality. Ruifu Chemical can supply a series of active bases and Grignard reagents. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Lithium Bis(trimethylsilyl)amide, Please contact: alvin@ruifuchem.com

Active Bases:

Potassium Bis(trimethylsilyl)amide	KHMDS	CAS 40949-94-8
Lithium Diisopropylamide	LDA	CAS 4111-54-0
Sodium Bis(trimethylsilyl)amide	NaHMDS	CAS 1070-89-9
Lithium Bis(trimethylsilyl)amide	LiHMDS	CAS 4039-32-1

4039-32-1 - Chemical Properties:

Chemical Name	Lithium Bis(trimethylsilyl)amide (1 M in Toluene)
Synonyms	LiHMDS; LHMDS; Hexamethyldisilazane Lithium Salt; Lithium Hexamethyldisilazide (1 M in Toluene)
Stock Status	In Stock, Commercial Production
CAS Number	4039-32-1
Molecular Formula	C6H18LiNSi2
Molecular Weight	167.33 g/mol
Boiling Point	55.0~56.0℃
Flash Point	48°F
Density	0.860 g/mL at 25℃(lit.)
Refractive Index n20/D	1.425(lit.)
Store Under Inert Gas	Store Under Inert Gas
Sensitive	Air Sensitive, Moisture Sensitive
Water Solubility	Hydrolysis
Hydrolytic Sensitivity	8: Reacts Rapidly with Moisture, Water, Protic Solvents
COA & MSDS	Available
Place of Origin	Shanghai, China
Brand	Ruifu Chemical

4039-32-1 - Specifications:

Items	Specifications	Results
Appearance	Yellow to Brown Liquid	Yellow Liquid
Concentration	0.95~1.1 mol/L	1 M in Toluene
Ethylbenzene (C6H5C2H4)	<8.0%	7.0%
Infrared Spectrum	Conforms to Structure	Conforms
Conclusion	The product has been tested and complies with the given specifications

Package/Storage/Shipping:

Package: Bottle, 25kg/Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light, fire and moisture, water.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

4039-32-1 - Risk and Safety:

Risk Codes R11 - Highly Flammable
R34 - Causes burns
R48/20 -
R63 - Possible risk of harm to the unborn child
R65 - Harmful: May cause lung damage if swallowed
R67 - Vapors may cause drowsiness and dizziness
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R35 - Causes severe burns
R20 - Harmful by inhalation
R62 - Possible risk of impaired fertility
R14 - Reacts violently with water
R40 - Limited evidence of a carcinogenic effect
R37 - Irritating to the respiratory system
R19 - May form explosive peroxides
Safety Description S9 - Keep container in a well-ventilated place.
S16 - Keep away from sources of ignition.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S29 - Do not empty into drains.
S33 - Take precautionary measures against static discharges.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label.
S57 - Use appropriate container to avoid environmental contamination.
S43 - In case of fire use ... (there follows the type of fire-fighting equipment to be used.)
UN IDs UN 2925 4.1/PG 2
WGK Germany 3
FLUKA BRAND F CODES 10-23
TSCA Yes
HS Code 2931900090
Hazard Class 4.3
Packing Group II

4039-32-1 - Application:

Lithium Bis(trimethylsilyl)amide (1 M in Toluene) (LiHMDS) (CAS: 4039-32-1) is used as nonnucleophilic base to generate kinetic ketone and ester enolates. It is considerably more selective than LDA and undesired reductions (e.g., of nonenolizable ketones observed in the case of LDA) can be avoided by using LHMDS.
Lithium Bis(trimethylsilyl)amide is generally used in organic synthesis as a non-nucleophilic strong Bronsted base.
Used for aldehyde alcohol condensation, is a commonly used organic base
Lithium Bis(trimethylsilyl)amide can be used as a non-nucleophilic strong base, which can be used to form enol reactions, enol ester stereospecific Claisen rearrangement reaction, the reaction of converting aldehyde into silimine, the reaction of glycidyl ester, the reaction of β lactam, the selective cleavage reaction of aryl alkyl ether, it is mainly used in laboratory research and development process and organic synthesis process.