L-Lysine Acetate CAS 57282-49-2 Assay 98.5~101.0% (Titration)
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of L-Lysine Acetate (L-Lysine Monoacetate, H-Lys-OH AcOH) (CAS: 57282-49-2) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in L-Lysine Acetate, Please contact: alvin@ruifuchem.com
| Chemical Name | L-Lysine Acetate |
| Synonyms | L-Lysine Acetate Salt; Laevo-Lysine Acetate; L-Lysine Monoacetate; H-Lys-OH AcOH; L-Lys AcOH; L-Lysine Ac; (S)-2,6-Diaminohexanoic Acid Acetate Salt; (S)-2,6-Diaminohexanoic Acid Monoacetate; Lysine Acetate |
| Stock Status | In Stock |
| CAS Number | 57282-49-2 |
| Molecular Formula | C6H14N2O2·C2H4O2 |
| Molecular Weight | 206.24 |
| Solubility | Freely Soluble in Water, Very Slightly Soluble in Ethanol (96 percent) |
| Storage Temp. | Sealed in Dry, Store at Room Temperature |
| COA & MSDS | Available |
| Classification | Amino Acid Derivatives |
| Brand | Ruifu Chemical |
| WGK Germany | 2 |
| RTECS | OL5644200 |
| HS Code | 2922419000 |
| Items | Inspection Standards | Results |
| Appearance | White Crystals or Crystalline Powder; Slightly Acid Taste | Conforms |
| Identification | Infrared Absorption Spectrum | Conforms |
| Specific Rotation [α]20/D | +8.5° to +10.0°(C=10, H2O) |
+9.1° |
| State of Solution (Transmittance) | Clear and Colorless ≥98.0% (430 nm) | 99.0% |
| Chloride (Cl) | ≤0.020% | <0.020% |
| Sulfate (SO4) | ≤0.020% | <0.020% |
| Ammonium (NH4) | ≤0.020% | <0.020% |
| Iron (Fe) | ≤10ppm | <10ppm |
| Heavy Metals (Pb) | ≤10ppm | <10ppm |
| Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
| Other Amino Acids | Conforms | Conforms |
| Loss on Drying | ≤0.20% (at 80℃ for 3 Hours) | 0.16% |
| Residue on Ignition (Sulfated) | ≤0.10% | 0.07% |
| Assay | 98.5 to 101.0% (Titration) | 99.5% |
| pH Test | 6.5 to 7.5 (1.0g in 10ml of H2O) | 7.0 |
| Origin | Non-Animal Source | Conforms |
| Residual Solvents | Conforms | Conforms |
| Conclusion | This Product by Inspection Accords with the Standard of AJI97 | |
| Main Uses | Amino Acids; Food Additives; Pharmaceutical Intermediates; Nutritional Supplement | |
L-Lysine Acetate (CAS: 57282-49-2) AJI 97 Test Method
Identification: Compare the infrared absorption spectrum of the sample with that of the standard by potassium bromide disc method.
Specific Rotation [α]20/D: Dried Sample, C=10, H2O
State of Solution (Transmittance): 1.0g in 10ml of H2O spectrophotometer, 430nm, 10nm cell thickness.
Chloride (Cl): 0.7g, A-1, ref: 0.40ml of 0.01mol/L HCl
Ammonium (NH4): B-1
Sulfate (SO4): 1.2g, (1), ref: 0.50ml of 0.005mol/L H2SO4
Iron (Fe): 1.5g, (1), ref: 1.5ml of Iron Std. (0.01mg/ml)
Heavy Metals (Pb): 2.0g, (1), pH=7, ref: 2.0ml of Pb Std. (0.01mg/ml)
Arsenic (As2O3): 2.0g, (1), ref: 2.0ml of As2O3 Std.
Other Amino Acids: Test Sample: 50μg, F-1-a, control: L-Lys AcOH 0.25μg
Loss on Drying: at 80℃ for 3 hours.
Assay: Dried sample, 110mg, (1), 3ml of formic acid, 50ml of glacial acetic acid, 0.1mol/L HCLO4 1ml=10.312mg C8H18N2O4
pH Test: 1.0g in 10ml of H2O
L-Lysine Acetate (CAS: 57282-49-2) USP35 Test Method
DEFINITION
Lysine Acetate contains NLT 98.0% and NMT 102.0% of L-Lysine Acetate (C6H14N2O2·C2H4O2), calculated on the dried basis.
IDENTIFICATION
A. INFRARED ABSORPTION <197K>
ASSAY
PROCEDURE
Sample: 100 mg of Lysine Acetate
Blank: Mix 3 mL of formic acid and 50 mL of glacial acetic acid.
Titrimetric system
(See Titrimetry <541>)
Mode: Direct titration
Titrant: 0.1 N perchloric acid VS
Endpoint detection: Potentiometric
Analysis: Dissolve the Sample in 3 mL of formic acid and 50mL of glacial acetic acid. Titrate with the Titrant. Perform the Blank determination.
Calculate the percentage of Lysine Acetate (C6H14N2O2·C2H4O2) in the Sample taken:
Result = {[(VS-VB) x N x F]/W} x100
VS= Titrant volume consumed by the Sample (mL)
VB= Titrant volume consumed by the Blank (mL)
N= actual normality of the Titrant (mEq/mL)
F= equivalency factor, 103.1 mg/mEq
W= Sample weight (mg)
Acceptance criteria: 98.50%~102.0% on the dried basis
IMPURITIES
RESIDUE ON IGNITION <281>: NMT 0.4%
CHLORIDE AND SULFATE, Chloride <221>
Standard solution: 0.50mL of 0.020 N hydrochloric acid
Sample: 0.73g of Lysine Acetate
Acceptance criteria: NMT 0.05%
CHLORIDE AND SULFATE, Sulfate <221>
Standard solution: 0.10 mL of 0.020 N sulfuric acid
Sample: 0.33 g of Lysine Acetate
Acceptance criteria: NMT 0.03%
IRON <241>: NMT 30ppm
HEAVY METALS, Method I <231>: NMT 15ppm
RELATED COMPOUNDS
Standard solution: 0.05 mg/mL of USP L-Lysine Acetate RS in water. [NOTE-This solution has a concentration equivalent to 0.5% of that of the Sample solution.]
Sample solution: 10mg/mL of Lysine Acetate in water
System suitability solution: 0.4 mg/mL each of USP L-Lysine Acetate RS and USP Arginine Hydrochloride RS
Chromatographic system
(See Chromatography <621>, Thin-Layer Chromatography.)
Mode: TLC
Adsorbent: 0.25-mm layer of chromatographic silica gel mixture
Application volume: 5μL
Developing solvent system: Isopropyl alcohol and ammonium hydroxide (7:3)
Spray reagent: 0.2 g of ninhydrin in a mixture of butyl alcohol and 2N acetic acid (95:5)
System suitability
Suitability requirements: The chromatogram of the System suitability solution exhibits two clearly separated spots.
Analysis
Samples: Standard solution, System suitability solution, and Sample solution.
Dry the plate between 100° and 105° until the ammonia completely disappears. Spray with Spray reagent, and heat between 100° and 105° for 15 min. Examine the plate under white light.
Acceptance criteria: Any secondary spot of the Sample solution is not larger or more intense than the principal spot of the Standard solution.
Individual impurities: NMT 0.5%
Total impurities: NMT 2.0%
SPECIFIC TESTS
OPTICAL ROTATION, Specific Rotation <781S>
Sample solution: 100 mg/mL in water
Acceptance criteria: +8.4° to +9.9°
LOSSON DRYING <731>: Dry a sample at 80℃ for 3 h: it loses NMT 0.2% of its weight.
ADDITIONAL REQUIREMENTS
PACKAGING AND STORAGE: Preserve in well-closed containers.
USP REFERENCE STANDARDS <11>
USP Arginine Hydrochloride RS
USP L-Lysine Acetate RS
Package: Fluorinated Bottle, 25kg/bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from light and moisture.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
L-Lysine Acetate (L-Lysine Monoacetate, H-Lys-OH AcOH) (CAS: 57282-49-2), L-Lysine Acetate Powder is classified as an essential amino acid for humans and must be supplied in the diet. The male adult's daily requirement is 12 mg per kg of body weight. It is extremely rare for a diet to contain insufficient quantities of lysine. Vegetarians who follow a macrobiotic diet and athletes who exercise vigorously on a frequent basis must take care to obtain sufficient L-lysine. Beans, peas and lentils are the best source of lysine.
Function
1. L-Lysine Acetate is an essential amino acid found in corns and legumes.
2. L-Lysine Acetate plays an important role in protein metabolism and is vital for growth of infants.
3. L-Lysine Acetate may also promote growth during recovery after prolonged exercise or after hard training sessions.
4. L-Lysine Acetate is one of the branch-chained amino acids, which can be used by muscles as an energy source.
Application
1. L-Lysine Acetate can be used for pharmaceutical ingredient, food additives, sports nutrient, cosmetic materials, etc.
2. L-Lysine Acetate is nutritional supplement, Amino acids. Mainly used for amino acid infusion, due to special wettability, also used in cold cream, cosmetics. L-Ornithine L-Asparate constitute the human body of several kinds of essential amino acid of protein a, for the construction of protein has a very important role..
3. The human body synthesis slower, shall prevail essential amino acids.
4. Can be used to strengthen the baby food, surgical patients after food.
5. With chemical raising agent making bread, add histidine, leucine, arginine can improve fragrance.
