L-Hydroxyproline CAS 51-35-4 (H-Hyp-OH) Assay 98.5~101.0% Factory

Short Description:

Chemical Name: L-Hydroxyproline

Synonyms: H-Hyp-OH; trans-4-Hydroxy-L-Proline

CAS: 51-35-4

Assay: 98.5~101.0%

Appearance: White Crystals or Crystalline Powder

Unnatural Amino Acids, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

51-35-4 - Description:

Ruifu Chemical is the leading manufacturer of L-Hydroxyproline (H-Hyp-OH) (CAS: 51-35-4). Ruifu Chemical has been supplying amino acids and derivatives more than 15 years. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service. Purchase L-Hydroxyproline, Please contact: alvin@ruifuchem.com

51-35-4 - Chemical Properties:

Chemical Name	L-Hydroxyproline
Synonyms	H-Hyp-OH; trans-4-Hydroxy-L-Proline; H-L-Hyp-OH; H-trans-Hyp-OH; L-Hyp-OH; trans-L-4-Hydroxyproline; (2S,4R)-4-Hydroxypyrrolidine-2-Carboxylic Acid
Stock Status	In Stock, Production Capacity 35 Tons per Month
CAS Number	51-35-4
Molecular Formula	C5H9NO3
Molecular Weight	131.13 g/mol
Melting Point	273℃(dec.)(lit.)
Sensitive	Air Sensitive
Solubility in Water	Almost Transparency
Storage Temp.	Cool & Dry Place (≤25℃)
COA & MSDS	Available
Category	Unnatural Amino Acids
Brand	Ruifu Chemical

51-35-4 - Specifications:

Items	Inspection Standards	Results
Appearance	White Crystals or Crystalline Powder	Complies
Identification	The infrared Absorption Spectrum	Complies
State Of Solution	≥95.0%	98.5%
Specific Rotation [α]20/D	-74.0° to -77.0° (C=4 in H2O)	-75.2°
pH	5.0~6.5	5.8
Chloride (Cl)	≤0.020%	<0.020%
Sulfate (SO4)	≤0.020%	<0.020%
Ammonium (NH4)	≤0.020%	<0.020%
Heavy Metals (Pb)	≤10ppm	<10ppm
Iron (Fe)	≤10ppm	<10ppm
Arsenic (As2O3)	≤1ppm	<1ppm
Other Amino Acids	Conforms	Conforms
Loss on Drying	≤0.20%	0.11%
Residue on Ignition	≤0.10%	0.08%
L-Hydroxyproline Assay	98.5~101.0%	99.4%
Conclusion	This Product by Inspection Accords with the AJI92 Standard

51-35-4 - Test Method:

According to AJI92 standard:
Specific rotation: dried sample, C=4, H2O
Transmittance Test: 1.0g in 10mL of H2O, spectrophotometer, 430nm, 10nm cell thickness.
Chloride (Cl): 0.7g, A-1, ref: 0.40ml of 0.01N HCl
Ammonium (NH4): A-1
Sulfate (SO4): 1.2g, (1), ref: 0.50mL of 0.01N H2SO4
Iron (Fe): 1.5g, ref: 1.5mL of Iron Std, (0.01mg/mL)
Heavy metals (Pb): 2.0g, (1), ref: 2.0mL of Pb Std, (0.01mg/mL)
Arsenic (As2O3): 2.0g, (1), ref: 2.0mL of As2O3 Std.
Other amino acids: test sample: 10μg G-1-a
Loss on drying: at 105℃ for 3 hours
Residue on ignition:
Assay Test: dried sample, 130mg, 3mL of formic acid, 50mL of glacial acetic acid, 0.1N HClO4, 1mL=13.113mg L-Hydroxyproline.
PH: 1.0g in 10mL of H2O

51-35-4 - Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2-8℃) and well-ventilated warehouse away from incompatible substances. Keep away from direct sun light; away from fire and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

51-35-4 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

51-35-4 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

51-35-4 - Risk and Safety:

Risk Codes
R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
Safety Description
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S27 - Take off immediately all contaminated clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
RTECS TW3586500
TSCA Yes
HS Code 2922491990
Hazard Class IRRITANT

51-35-4 - Application:

L-Hydroxyproline (H-Hyp-OH) (CAS: 51-35-4), a non-essential amino acid, used in peptide synthesis, pharmaceutical intermediates, biochemical reagents, chemical reagents.
L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is used as an intermediate for a range of pharmaceutical active ingredients.
L-Hydroxyproline is the main raw material of antiviral drug Azanavir, it has high application value. L-Hydroxyproline is generally used as a food additive (used as a sweetener), and the use of a relatively large amount as an intermediate for the side chain of Peinan in medicine.
Flavor enhancer, nutrition enhancer, fragrance. Mainly used for fruit juice, cool drinks, nutritious drinks, etc.