HO-EPCP CAS 62893-24-7 Purity >98.0 (HPLC) Cefoperazone Sodium Intermediate

Short Description:

Name: (R)-(-)-α-[[(4-Ethyl-2,3-Dioxo-1-Piperazinyl)carbonyl]amino]-4-Hydroxybenzeneacetic Acid

Synonyms: HO-EPCP 

CAS: 62893-24-7

Purity: >98.0% (HPLC) 

Appearance: White Powder or Crystals

Intermediate of Cefoperazone and Cefoperazone Sodium 

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E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (R)-(-)-α-[[(4-Ethyl-2,3-Dioxo-1-Piperazinyl)carbonyl]amino]-4-Hydroxybenzeneacetic Acid (HO-EPCP) (CAS: 62893-24-7) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name (R)-(-)-α-[[(4-Ethyl-2,3-Dioxo-1-Piperazinyl)carbonyl]amino]-4-Hydroxybenzeneacetic Acid
Synonyms (R)-(-)-alpha-[[(4-Ethyl-2,3-Dioxo-1-Piperazinyl)carbonyl]amino]-4-Hydroxybenzeneacetic Acid; (R)-(-)-2-(4-Ethyl-2,3-Dioxopiperazine-1-Carboxamido)-2-(4-Hydroxyphenyl)acetic Acid; (2R)-2-[(4-Ethyl-2,3-Dioxopiperazinyl)carbonylamino]-2-(4-Hydroxyphenyl)acetic Acid; HO-EPCP
Impurity  Cefoperazone Impurity 2 
CAS Number 62893-24-7 
CAT Number RF2482
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C15H17N3O6 
Molecular Weight 335.32   
Melting Point 203℃(dec.)(lit.) 
Density 1.456 g/mL
Solubility  Slightly Soluble in Methanol
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White Powder or Crystals
Purity / Analysis Method >98.0% (HPLC) 
Purity / Analysis Method >98.0% (Neutralization Titration) 
Specific Rotation [a]20/D -90.0° to -80.0° (C=1 in MeOH)
Loss on Drying <1.00%
Total Impurities <2.00%
Infrared Spectrum Conforms to Structure
Proton NMR Spectrum Conforms to Structure
Test Standard Enterprise Standard
Usage Intermediate of Cefoperazone (62893-19-0) and Cefoperazone Sodium (CAS 62893-20-3)

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Excellent quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

(R)-(-)-α-[[(4-Ethyl-2,3-Dioxo-1-Piperazinyl)carbonyl]amino]-4-Hydroxybenzeneacetic Acid (HO-EPCP) (CAS: 62893-24-7) is an intermediate used to prepare Cephalosporin derivatives with activities against both Gram-positive and Gram-negative bacteria. HO-EPCP is an intermediate of Cefoperazone (62893-19-0) and Cefoperazone Sodium (CAS 62893-20-3). Cefoperazone Sodium is a third-generation, antipseudomonalcephalosporin that resembles piperacillinchemically and microbiologically. It is active against manystrains of P. aeruginosa, indole-positive Proteus spp., Enterobacter spp., and S. marcescens that are resistant tocefamandole. It is less active than cephalothin against Gram-positive bacteria and less active than cefamandoleagainst most of the Enterobacteriaceae. Like Piperacillin, Cefoperazone is hydrolyzed by many of the β-lactamasesthat hydrolyze Penicillins. Unlike Piperacillin, however, it is resistant to some (but not all) of the β-lactamases thathydrolyze Cephalosporins. Cefoperazone is excreted primarily in the bile. Hepaticdysfunction can affect its clearance from the body.

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