H-Lys(Z)-OH CAS 1155-64-2 Nε-Cbz-L-Lysine Purity >98.0% (HPLC) Factory

Short Description:

Chemical Name: Nε-Cbz-L-Lysine

Synonyms: H-Lys(Z)-OH

CAS: 1155-64-2

Purity: >98.0% (HPLC)

Appearance: White Powder

Amino Acids and Derivatives, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Nε-Cbz-L-Lysine (H-Lys(Z)-OH) (CAS: 1155-64-2) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. Purchase H-Lys(Z)-OH, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	Nε-Cbz-L-Lysine
Synonyms	H-Lys(Z)-OH; N(epsilon)-Cbz-L-Lysine; Nε-Carbobenzoxy-L-Lysine; N(epsilon)-Carbobenzoxy-L-Lysine; Nε-Benzyloxycarbonyl-L-Lysine; N(epsilon)-Benzyloxycarbonyl-L-Lysine; N6-Cbz-L-Lysine; Lysine(Z)-OH
Stock Status	In Stock
CAS Number	1155-64-2
Molecular Formula	C14H20N2O4
Molecular Weight	280.32 g/mol
Melting Point	230.0~260.0℃
Density	1.1816
Solubility in Hot HCl	Almost Transparency
Storage Temp.	Cool & Dry Place (2~8℃)
COA & MSDS	Available
Category	Amino Acids and Derivatives
Brand	Ruifu Chemical

Safety Information:

Safety Statements	24/25 - Avoid contact with skin and eyes.	Hazard Class	IRRITANT
WGK Germany	3	HS Code	2922491990

Specifications:

Items	Inspection Standards	Results
Appearance	White Powder	White Powder
Specific Rotation [α]20/D	+14.0°±2.0° (C=0.5 1N HCl)	+15.4°
Melting Point	230.0~260.0℃	232.0~233.5℃
Loss on Drying	<1.00% (80℃, 2h)	0.41%
H-Lys(Z)-OH Purity	>98.0% (HPLC)	99.14%
Clarity of Solution	0.3 gram in 2ml TFA Clear Solution	Complies
NMR Spectrum 1H	Conforms to Structure	Complies
Infrared Spectrum	Conforms to Structure	Complies
Conclusion	The product has been tested & complies with the given specifications

Package & Storage:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.

Method of Analysis:

Column: 4.6*250mm, Sinochrom ODS-BP 5μm
Solvent A: 0.1% trifluoroacetic in 100% water
Solvent B: 0.1% trifluoroacetic in 100% acetonitrile
Gradient A B
0.01min 90% 10%
20.0min 0% 100%
25.0min stop
Flow rate: 1.0ml/min
Wavelength: 220nm
Sample Description: 3mg/ml ACN:H2O=1:1
Volume: 15μl

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

Application:

Nε-Cbz-L-Lysine (H-Lys(Z)-OH) (CAS: 1155-64-2) is an amino acid derivative and an intermediate in chiral organic synthesis. Its main purpose is to participate as a molecular skeleton in the synthesis of chiral drug molecules and biologically active molecules. In addition, the carboxyl group in Nε-Cbz-L-Lysine can undergo esterification in the presence of an amino group. The ester group protected by benzyl in the molecular structure can be easily removed under acidic conditions, releasing free carboxyl groups.
Synthesis route For the synthesis of Nε-Cbz-L-Lysine, the conventional synthesis method is from the lysine of its corresponding configuration and the acid chloride of another fragment Starting from the reaction of the amino group and the acid chloride to generate the corresponding amide to obtain the target product Nε-Cbz-L-Lysine. This route requires the addition of alkali as an acid binding agent, such as sodium hydroxide.
Environmental hazards as an organic amine, Nε-Cbz-L-Lysine is harmful to the water environment and cannot allow undiluted or large amounts of products to contact groundwater, waterways or sewage systems.