H-Glu(OtBu)-OH CAS 2419-56-9 Purity >98.0% (HPLC) Factory

Short Description:

Chemical Name: L-Glutamic Acid 5-tert-Butyl Ester

Synonyms: H-Glu(OtBu)-OH

CAS: 2419-56-9

Purity: >98.0% (HPLC)

Appearance: White Powder

Amino Acids and Derivatives, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Send email to us

Product Detail

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of H-Glu(OtBu)-OH (CAS: 2419-56-9) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. Purchase H-Glu(OtBu)-OH, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	L-Glutamic Acid 5-tert-Butyl Ester
Synonyms	H-Glu(OtBu)-OH; L-Glu(OtBu)-OH; L-Glutamic Acid γ-tert-Butyl Ester; 5-tert-Butyl L-Glutamate; (2S)-2-Amino-5-tert-Butoxy-5-Oxopentanoic Acid; (S)-2-Amino-5-tert-Butoxy-5-Oxopentanoic Acid
Stock Status	In Stock
CAS Number	2419-56-9
Molecular Formula	C9H17NO4
Molecular Weight	203.24 g/mol
Melting Point	182℃(lit.)
Density	0.992 g/cm3
Sensitive	Heat Sensitive
Solubility	Sparingly Soluble in Water; Practically Insoluble in Ethanol or Ether
Storage Temp.	Cool & Dry Place (2~8℃)
COA & MSDS	Available
Category	Amino Acids and Derivatives
Brand	Ruifu Chemical

Specifications:

Items	Inspection Standards	Results
Appearance	White Powder	White Powder
Specific Rotation [α]20/D	+19.0°±2.0° (C=1 in AcOH)	+20.4°
Melting Point	~170.0℃	171.2~171.8℃
TLC	≥98.0%	>98.0%
Element Analysis (C、H、N)	≤5.0%	<5.0%
Clarity of Solution	0.3 gram in 2ml AcOH Clear Solution	Complies
Water Content (K.F.)	≤6.00%	1.25%
Loss on Drying	≤5.00% (70°C, 2h)	0.48%
Purity / Analysis Method	>98.0% (HPLC)	99.12%
Mass Spectrum	In Accordance With the Standard	Complies
NMR Spectrum	In Accordance With the Standard	Complies
Conclusion	The product has been tested & complies with the given specifications

Package & Storage:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Heat sensitive. Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from heat, light and moisture.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

2419-56-9 - Risk and Safety:

Risk Codes
R22 - Harmful if swallowed
R24 - Toxic in contact with skin
Safety Description
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S25 - Avoid contact with eyes.
WGK Germany 3
HS Code 2922491990
Hazard Class IRRITANT

Application:

L-Glutamic Acid 5-tert-Butyl Ester (H-Glu(OtBu)-OH) (CAS: 2419-56-9) is a glutamic acid derivative, can be obtained by the reaction of glutamic acid and tert-butyl acetate.
Amino acids and derivatives, used in peptide synthesis, organic synthesis intermediates, pharmaceutical intermediates, biochemical reagents, chemical reagents.
Preparation add 2324g of tert-butyl acetate and 73.5g of glutamic acid into a 3000mL three-mouth bottle, stir, drop 160.8mL of perchloric acid, react at 10℃ for 48 hours, cool to 0℃, add 1000mL of water, extract take (the remaining tert-butyl acetate is extracted as solvent), neutralize with Na2CO3 to pH = 8~9, separate the liquid, then wash with 400 mL1% Na2CO3 aqueous solution three times, and concentrate the tert-butyl acetate layer under reduced pressure to obtain 42g of oil Glu(OtBu)2 with a yield of 32.4%. Add 42g of Glu(OtBu)2 into a 1000mL three-mouth bottle, then add 400mL of water and 11g of CuCl2, raise the temperature to 50℃, react for 12 hours, and prepare Cu[Glu(OtBu)]x(x = 1~2); When it is reduced to room temperature, add 19g of tetramethylethylenediamine and 100mL of dioxane, and then adjust the pH to 8~9 with triethylamine, L-Glutamic Acid 5-tert-Butyl Ester was prepared.