Fmoc-Gln(Trt)-OH CAS 132327-80-1 Purity >99.0% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Nα-Fmoc-Nδ-Trityl-L-Glutamine (Fmoc-Gln(Trt)-OH) (CAS: 132327-80-1) with high quality. Ruifu Chemical supplys a series of amino acids. We can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase Fmoc-Gln(Trt)-OH, Please contact: alvin@ruifuchem.com
| Chemical Name | Nα-Fmoc-Nδ-Trityl-L-Glutamine |
| Synonyms | Fmoc-Gln(Trt)-OH; Fmoc-L-Gln(Trt)-OH; Nalpha-Fmoc-Ndelta-Trityl-L-Glutamine; Nalpha-9-Fluorenylmethoxycarbonyl-Ndelta-Trityl-L-Glutamine |
| Stock Status | In Stock |
| CAS Number | 132327-80-1 |
| Molecular Formula | C39H34N2O5 |
| Molecular Weight | 610.7 g/mol |
| Melting Point | 150.0~170.0℃ |
| Density | 1.256±0.06 g/cm3 |
| Sensitive | Moisture Sensitive |
| Storage Temp. | Cool & Dry Place (2~8℃) |
| COA & MSDS | Available |
| Category | Fmoc-Amino Acids |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | White Powder | White Powder |
| Purity / Analysis Method | >99.0% (HPLC) | 99.57% |
| Specific Rotation [α]20/D | -14.5°±2.0° (C=1 in DMF) |
-14.1° |
| Melting Point | 150.0~170.0℃ | 158.9~159.3℃ |
| TLC | ≥98.0% | >98.0% |
| Element Analysis (C、H、N) | ≤5.0% | <5.0% |
| Optical Purity | <0.80% D-Enantiomer | Not Detectable |
| Clarity of Solution | 0.3 gram in 2ml DMF Clear Solution | Complies |
| Kaiser Test | <0.05% | <0.05% |
| Water by Karl Fischer | <0.50% | 0.13% |
| Residue on Ignition | <0.20% | Complies |
| Fmoc-β-Ala-OH | <0.50% (HPLC) | Complies |
| Fmoc-β-Ala-Gln(Trt) -OH | <0.10% (HPLC) | Complies |
| Fmoc-Gln(Trt)-Gln(Trt)-OH | <0.10% (HPLC) | Complies |
| Fmoc-Gln-OH | <0.10% (HPLC) | Complies |
| Assay Free Amino Acid | <0.20% (GC) | Complies |
| Ethyl Acetate | <0.50% (GC) | Complies |
| IR Spectrum | In Accordance With the Standard | Complies |
| Mass Spectrum | In Accordance With the Standard | Complies |
| NMR Spectrum | In Accordance With the Standard | Complies |
| Conclusion | The product has been tested & complies with the given specifications | |
1. Reaction Process:
2. The Residual Solvents:
Ethyl Acetate, Petroleum Ether
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols Xi - Irritant
Risk Codes R36/37/38 - Irritating to eyes, respiratory system and skin.
R53 - May cause long-term adverse effects in the aquatic environment
R43 - May cause sensitization by skin contact
Safety Description S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
S37 - Wear suitable gloves.
S24 - Avoid contact with skin.
WGK Germany 3
FLUKA BRAND F CODES 10-21
HS Code 2922491990
Nα-Fmoc-Nδ-Trityl-L-Glutamine (Fmoc-Gln(Trt)-OH) (CAS: 132327-80-1), is an amino acid derivative used in chemical synthesis and peptide chemistry.
Reaction type: Fmoc solid-phase peptide synthesis. Fmoc-amino acids, used in peptide synthesis, used as an organic synthesis intermediate, pharmaceutical intermediate, biochemical reagent or chemical reagent.
Fmoc-Gln(Trt)-OH in peptide synthesis prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Gln(Trt)-OH also has better solubility properties than Fmoc-Gln-OH. Fmoc-Gln(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Gln-OH is much less soluble in Dimethylformamide (DMF).
Fmoc-Gln(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Gln. Coupling can be performed by standard procedures. The trityl-protecting group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp.
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