Fmoc-D-Leu-OH CAS 114360-54-2 N-Fmoc-D-Leucine Purity >99.0% (HPLC) Factory

Short Description:

Chemical Name: N-Fmoc-D-Leucine

Synonyms: Fmoc-D-Leu-OH 

CAS: 114360-54-2

Purity: >99.0% (HPLC)

Appearance: White Powder

Fmoc-Amino Acids, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Product Detail

Related Products

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of N-Fmoc-D-Leucine (Fmoc-D-Leu-OH) (CAS: 114360-54-2) with high quality. Ruifu Chemical supplys a series of amino acids. We can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase Fmoc-D-Leu-OH, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name N-Fmoc-D-Leucine 
Synonyms Fmoc-D-Leu-OH; Fmoc-D-Leucine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-Leucine; N-9-Fluorenylmethoxycarbonyl-D-Leucine; (R)-Fmoc-2-Amino-4-Methylpentanoic Acid
Stock Status In Stock, Production Capacity to Tons per Month
CAS Number 114360-54-2 
Molecular Formula C21H23NO4
Molecular Weight 353.42 g/mol
Melting Point 153.0 to 160.0℃ 
Density 1.207±0.06 g/cm3  
Water Solubility  Insoluble in Water 
Storage Temp.  Cool & Dry Place (2~8℃) 
COA & MSDS Available
Category   Fmoc-Amino Acids 
Brand Ruifu Chemical

Safety Information:

Safety Statements S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. 
WGK Germany 3                           HS Code           2922491990                        
F 10

Specifications:

Items Inspection Standards Results
Appearance White Powder  White Powder
Specific Rotation [α]20/D +25.0°±2.0° (C=1 in DMF)
+25.9°
Melting Point 153.0 to 160.0℃ 154.2℃
TLC ≥98.0% >98.0%
Element Analysis (C、H、N) ≤5.0% <5.0%
Optical Purity <0.50% L-Enantiomer Complies
Clarity of Solution 0.3 gram in 2ml DMF Clear Solution Complies
Kaiser Test <0.05% <0.05%
Water by Karl Fischer  <1.00% 0.103%
Loss on Drying <1.00% (80℃, 2h) 0.28%
Purity / Analysis Method >99.0% (HPLC)  99.64% 
Mass Spectrum In Accordance With the Standard Complies 
NMR Spectrum In Accordance With the Standard Complies 
Conclusion The product has been tested & complies with the specifications

Package & Storage:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

N-Fmoc-D-Leucine (Fmoc-D-Leu-OH) (CAS: 114360-54-2) is the N-Fmoc protected form of D-Leucine. D-Leucine, an unnatural isomer of L-Leucine. Fmoc-amino acids, used in peptide synthesis, used as an organic synthesis intermediate, pharmaceutical intermediate, biochemical reagent or chemical reagent.
A convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-Tryptophan methyl ester and N-Fmoc-D-Leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.
Synthesis method In the presence of alkali, 9-Fluorenomethoxycarbonyl chloride reacts with leucine to obtain Fmoc-D-Leucine. This method is simple to operate, The method of preparing Fmoc-D-Leucine with mild reaction conditions, high yield and wide applicability. 

  • Write your message here and send it to us