Ethyl Trifluoroacetate CAS 383-63-1 Purity >99.5% (GC)

Short Description:

Chemical Name: Ethyl Trifluoroacetate

Synonyms: TFAE; Trifluoroacetic Acid Ethyl Ester

CAS: 383-63-1

Purity: >99.5% (GC)

Appearance: Colorless Transparent Liquid

High Quality, Commercial Production

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Ethyl Trifluoroacetate (CAS: 383-63-1) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	Ethyl Trifluoroacetate
Synonyms	TFAE; Trifluoroacetic Acid Ethyl Ester; Ethyl 2,2,2-Trifluoroacetate; Ethyl α,α,α-Trifluoroacetate; TFAEt
CAS Number	383-63-1
CAT Number	RF2873
Stock Status	In Stock, Production Capacity 600MT/Year
Molecular Formula	C4H5F3O2
Molecular Weight	142.08
Melting Point	-78℃
Boiling Point	60.0~62.0℃(lit.)
Flash Point	-7℃
Density	1.194 g/mL at 25℃(lit.)
Refractive Index n20/D	1.307(lit.)
Sensitive	Moisture Sensitive
Solubility in Water	Hydrolysis
Solubility	Slightly Miscible With Water. Miscible With Chloroform and Methanol
COA & MSDS	Available
Sample	Available
Brand	Ruifu Chemical

Specifications:

Item	Specifications	Specifications
Appearance	Colorless Transparent Liquid	Colorless Transparent Liquid
Purity / Analysis Method	>99.5% (GC)	99.823% (GC)
Water (by Karl Fischer)	<0.10%	0.002%
Density (20℃)	1.190~1.195	Complies
Refractive Index n20/D	1.305~1.310	Complies
Fluoride	<0.10%	0.004%
Chloride	<0.10%	0.003%
Sulphate	<0.10%	0.003%
Infrared Spectrum	Conforms to Structure	Complies
Test Standard	Enterprise Standard	Complies

Package & Storage:

Package: Bottle, 25kg/Drum, 200kg/Drum or according to customer's requirement

Storage Condition: Moisture Sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases and strong acids.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

383-63-1 - Risk and Safety:

Risk Codes R11 - Highly Flammable
R22 - Harmful if swallowed
R37/38 - Irritating to respiratory system and skin.
R41 - Risk of serious damage to eyes
R34 - Causes burns
Safety Description S9 - Keep container in a well-ventilated place.
S16 - Keep away from sources of ignition.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/39 -
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs UN 1993 3/PG 2
WGK Germany 1
TSCA T
HS Code 2915900090
Hazard Note Flammable/Corrosive
Hazard Class 3
Packing Group II

383-63-1 - Introduction:

Ethyl Trifluoroacetate (CAS: 383-63-1) is a volatile, colorless and transparent liquid with the smell of ester, easily soluble in ether, ethanol, chloroform, slightly soluble in water, and slowly hydrolyzed in water. The vapor of ethyl trifluoroacetate can form an explosive mixture with air. It is easy to burn and explode when exposed to open flames and high heat. It decomposes and releases highly toxic flue gas when exposed to high heat, which reacts violently with oxidant.

383-63-1 - Application:

Ethyl Trifluoroacetate (CAS: 383-63-1) is widely used in the synthetic process of pharmaceuticals, pesticides, agrochemicals and organic intermediates. Ethyl Trifluoroacetate is an intermediate used in the synthesis of various pharmaceutically active molecules and agricultural products. Ethyl Trifluoroacetate is also useful for the preparation of tri fluoroacylated compounds.

Ethyl Trifluoroacetate, as an important organic chemical raw material, has a wide range of applications in the synthesis of organic fluorine compounds, medicines, pesticides, liquid crystals and dyes. The specific applications are as follows:(1) In medicine, mainly used in the production of anti-inflammatory drugs for osteoarthritis, anti-tumor drugs for the treatment of colon and rectal cancer, cardiovascular and cerebrovascular drugs-Lenopril, etc.;(2) In terms of pesticides, it is mainly used to make cell division Inhibitors are used to kill grass and broadleaf grass in cotton and peanut fields;(3) In terms of organic synthesis, because Ethyl Trifluoroacetate has a low removal rate in a mild environment, it is often used for the protection of amino groups.

383-63-1 - Production Method:

Ethyl Trifluoroacetate (CAS: 383-63-1) is obtained by esterification of trifluoroacetic acid and ethanol. After the trifluoroacetic acid is cooled, absolute ethanol is added under stirring, and the reaction is exothermic. After the heat release is stopped, concentrated sulfuric acid is slowly added. After heating and refluxing for half an hour, fractionation is carried out, and the fraction at 62-64℃ is collected to obtain ethyl trifluoroacetate. 94% yield.