Cinchonine CAS 118-10-5 Purity ≥98.0% (T) High Purity

Short Description:

Chemical Name: Cinchonine 

CAS: 118-10-5

Purity: ≥98.0% (Nonaqueous Titration)

Appearance: White Crystals or White Crystalline Powder

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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118-10-5 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Cinchonine (CAS: 118-10-5) with high quality. Ruifu Chemical has been supplying Cinchonine more than 15 years.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Cinchonine or other products, please contact us by e-mail: alvin@ruifuchem.com

118-10-5 - Chemical Properties:

Chemical Name Cinchonine
Synonyms (+)-Cinconine; (8R,9S)-Cinchonine; D-Cinchonine; (9s)-Cinchonan-9-o; (9S)-Cinchonan-9-ol; (8alpha,9S)-Cinchonan-9-ol
Stock Status In Stock, Commercial Production  
Purity (Nonaqueous Titration)  ≥98.0% (~85% Cinchonine + ~15% Dihydrocinchonine)
CAS Number 118-10-5
Molecular Formula C19H22N2O
Molecular Weight 294.40 g/mol
Melting Point 255.0-265.0℃ 
Specific Rotation [α]20/D +218.0° - +228.0° (C=0.5, EtOH)
Sensitive Light Sensitive 
Water Solubility  Insoluble in Water 
Solubility  Slightly Soluble in Alcohol
Storage Temperature Store Long-Term in a Cool and Dry Place 
Stability Stable, but may be light sensitive. Incompatible with strong oxidizing agents
COA & MSDS Available
Sample  Available
Shelf Life 2 Years If Sealed and Stored Properly
Origin of Product    Shanghai, China
Product Categories
Pharmaceutical Intermediates
Brand Ruifu Chemical
Quality Standard Enterprise Standard

118-10-5 - Specifications:

Items Specifications  Results
Appearance White Crystals or White Crystalline Powder Conforms  
Melting Point 255.0-265.0℃ 257.8-258.4℃
Specific Rotation [α]20/D +218.0° - +228.0° (C=0.5 in EtOH) +219.91°
Loss on Drying ≤1.00% 0.56%
Sulfate Ash ≤0.10% Conforms 
Quinine ≤3.00% (HPLC) Conforms 
Purity (Nonaqueous Titration) ≥98.0% (Calculated on the Dried Basis) 100.4%
IR Spectrum Conforms to Structure   Conforms   
Conclusion The product has been tested and complies with the given specifications

118-10-5 - Package/Storage/Shipping:

Package: Fluorinated bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2-8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

118-10-5 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

118-10-5 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

118-10-5 - Risk and Safety:

Hazard Symbols Xn - Harmful
Risk Codes
R20/22 - Harmful by inhalation and if swallowed.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S36/37 - Wear suitable protective clothing and gloves.
UN IDs 1544
WGK Germany 3
RTECS GD3500000
FLUKA BRAND F CODES 8-34
HS Code 2934999099
Hazard Class 6.1(b)
Packing Group III

118-10-5 - Introduction:

Cinchonine (CAS: 118-10-5) is a quinoline-type alkaloid, a kind of cinchona alkaloid. Cinchonine has a wide range of biological activities, including anti-inflammatory, anti-bacterial, anti-fungal, antimalarial, anti-cancer properties.

118-10-5 - Function of Cinchonine :

1. Cinchonine (CAS: 118-10-5) is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.
2. Cinchonine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.
3. Cinchonine was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
4. Cinchonine is also very useful for some muscle diseases, especially nocturnal leg cramps and congenital myotonia, because it directly acts on muscle membranes and sodium channels.  

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