2,4-Diamino-6-(Hydroxymethyl)pteridine HCl Hydrate CAS 73978-41-3 Methotrexate Intermediate Purity >97.0%

Short Description:

2,4-Diamino-6-(Hydroxymethyl)pteridine HCl Hydrate

CAS: 73978-41-3

Purity: >97.0% 

Appearance: Yellow or Brown-Yellow Powder

Intermediate of Methotrexate (CAS: 59-05-2) 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 2,4-Diamino-6-(Hydroxymethyl)pteridine Hydrochloride Hydrate (CAS: 73978-41-3) with high quality, intermediate of Methotrexate (CAS: 59-05-2). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Methotrexate Intermediates, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name 2,4-Diamino-6-(Hydroxymethyl)pteridine Hydrochloride Hydrate  
Synonyms 2,4-Diamino-6-(Hydroxymethyl)pteridine Hydrochloride; 2,4-Diamino-6-(Hydroxymethyl)pteridine HCl; (2,4-Diaminopteridin-6-yl)methanol Hydrochloride; (2,4-Diamino-6-Pteridinyl)methanol Hydrochloride Hydrate
Impurity  Methotrexate EP Impurity A
Stock Status In Stock, Commercial Production  
CAS Number 73978-41-3
CAS Free Base 945-24-4
Molecular Formula C7H8N6O.HCl.H2O
Molecular Weight 246.66 g/mol
Melting Point 220℃(lit.)  
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Category   Intermediate of Methotrexate (CAS: 59-05-2)  
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance Yellow or Brown-Yellow Powder  Complies      
Water by Karl Fischer  <5.00% 4.3% 
Heavy Metals (Pb) ≤30ppm <16ppm 
Purity  >97.0%  98.3% 
Infrared Spectrum Consistent with Structure Complies 
1 H NMR Spectrum  Consistent with Structure Complies
Conclusion The product has been tested & complies with the given specifications

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory AuditFactory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
TransportationBy Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom SynthesisCan provide custom synthesis services to best fit your research needs.
Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

73978-41-3 - Safety Information:

Risk Codes
R36/37/38 - Irritating to eyes, respiratory system and skin.
R36 - Irritating to the eyes
R22 - Harmful if swallowed
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany 3
HS Code 2934999099

73978-41-3 - Application:

2,4-Diamino-6-(Hydroxymethyl)pteridine Hydrochloride Hydrate (CAS: 73978-41-3) is used as an intermediate of Methotrexate (CAS: 59-05-2). Methotrexate is a drug used for the treatment of cancer, also known as cytotoxic drugs. In order to reduce its cytotoxicity, it can be used in conjunction with calcium leucovorin. It is primarily used for the treatment of acute leukemia (acute lymphocytic leukemia), breast cancer, malignant mole and choriocarcinoma, head and neck cancer, bone cancer, leukemia, spinal cord meningeal infiltration, lung cancer, reproductive system cancer, liver cancer, refractory psoriasis vulgaris, dermatomyositis, body myositis, ankylosing spondylitis inflammation, Crohn's disease, psoriasis and psoriatic arthritis, Behcet's disease and autoimmune disease.

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