N-Desbutyl Bupivacaine CAS 15883-20-2 (2′,6′-Pipecoloxylidide) Assay 98.0~102.0% Factory

Short Description:

N-(2,6-Dimethylphenyl)piperidine-2-Carboxamide

Synonyms: N-Desbutyl Bupivacaine; 2′,6′-Pipecoloxylidide

CAS: 15883-20-2

Assay: 98.0~102.0% (On Dried Basis) 

Appearance: White or Almost White Powder

Intermediate of Ropivacaine & Bupivacaine 

Contact: Dr. Alvin Huang 

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Product Detail

Related Products

Product Tags

Description:

Ruifu Chemical is the leading manufacturer of N-(2,6-Dimethylphenyl)piperidine-2-Carboxamide (N-Desbutyl Bupivacaine; 2',6'-Pipecoloxylidide) (CAS: 15883-20-2) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name N-(2,6-Dimethylphenyl)piperidine-2-Carboxamide 
Synonyms N-Desbutyl Bupivacaine; 2',6'-Pipecoloxylidide; Desbutylbupivacaine; Pipecolinoyl-2,6-Xylidide; (RS)-N-(2,6-Dimethylphenyl)piperidine-2-Carboxamide
Impurity  Bupivacaine USP Related Compound B; Bupivacaine EP Impurity B
Stock Status In Stock, Commercial Production  
CAS Number 15883-20-2
Molecular Formula C14H20N2O
Molecular Weight 232.33 g/mol
Melting Point 110.0 to 117.0℃ 
Density 1.087±0.06 g/cm3 
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance White or Almost White Powder White Powder 
Melting Point 110.0 to 117.0℃ 115.0~116.0℃
Loss on Drying ≤0.50% 0.10% 
Residue on Ignition ≤0.10% 0.08% 
Related Substances
2-Picolinic Acid ≤0.10% 0.0003%
2,6-Dimethylaniline ≤10ppm Not Detected
N-(2′,6′-Dimethylphenl)-2-Pyridine Carboxamide ≤0.10% 0.002%
Individual Unspecified Impurity ≤0.30% 0.06%
Total Impurities ≤0.50% 0.23%
Residual Solvents
Ethanol  ≤5000ppm Not Detected
Benzene   ≤2ppm Not Detected
Toluene  ≤890ppm 74ppm
N-Methyl-Pyrrolidinone ≤520ppm Not Detected
Assay 98.0%~102.0% (on the Dried Basis) 99.4%
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

15883-20-2 - Safety Information:

Risk Codes 25 - Toxic if swallowed
Safety Description 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs UN 2811 6.1 / PGIII
RTECS TM6076000
HS Code 2942000000

15883-20-2 - Application:

N-(2,6-Dimethylphenyl)piperidine-2-Carboxamide (N-Desbutyl Bupivacaine; 2',6'-Pipecoloxylidide) (CAS: 15883-20-2) is an intermediate of Ropivacaine (CAS: 84057-95-4) and Bupivacaine (CAS: 2180-92-9).
Ropivacaine is an aminoamide local anaesthetic drug commonly marketed by AstraZeneca under the trade name Naropin. Naropin was launched in 1996 in Australia, Denmark, Finland, the Netherlands and Sweden as a local anesthetic. Ropivacaine is used as a local (in only one area) anesthesia for a spinal block, also called an epidural. The medication is used to provide anesthesia during a surgery or C-section, or to ease labor pains.
Bupivacaine is a sodium channel blocker, local anesthetic. Bupivacaine is used in infiltration, spinal, and epidural anesthesia in blocking nerve transmission. Its most distinctive property is its long-lasting action. It is used for surgical intervention in urology and in lower thoracic surgery from 3 to 5 h in length, and in abdominal surgery lasting from 45 to 60 min. It is used to block the trifacial nerve, the sacral and brachial plexuses, in resetting dislocations, in epidural anesthesia, and during Cesarian sections. 

  • Write your message here and send it to us