Lurasidone Hydrochloride Intermediate CAS 14805-29-9 Purity ≥99.0% (HPLC)

Short Description:

Chemical Name: (3aR,4S,7R,7aS)-rel-Hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione

CAS: 14805-29-9

Appearance: White to Almost White Powder

Purity: ≥99.0% (HPLC)

Intermediate of Lurasidone Hydrochloride (CAS 367514-88-3), an antipsychotic used for treatment of schizophrenia. 

Contact: Dr. Alvin Huang 

Mobile/Wechat/WhatsApp: +86-15026746401

E-mail: alvin@ruifuchem.com


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Lurasidone Hydrochloride Intermediates:

14805-29-9 - Chemical Properties:

Chemical Name (3aR,4S,7R,7aS)-rel-Hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione
Synonyms exo-2,3-Norbornanedicarboximide; Lurasidon Hydrochloride Intermediate
CAS Number 14805-29-9
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C9H11NO2
Molecular Weight 165.19
Melting Point 150.0~154.0℃
Density 1.285
Shipping Condition Shipped Under Ambient Temperature as Non-Hazardous Chemical
COA & MSDS Available
Place of Origin Shanghai, China 
Brand Ruifu Chemical

14805-29-9 - Specifications:

Item Specifications
Appearance White to Almost White Powder
Melting Point 150.0~154.0℃
Differentiate H-NMR
Related Compound ≤0.50%
Endo Isomer ≤0.15%
Impurity A ≤0.10% (3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione
Max. Single Impurity ≤0.30%
Total Impurities ≤1.00%
Water Content ≤1.00%
Heavy Metals ≤20ppm
Purity / Analysis Method ≥99.0% (HPLC)
Test Standard Enterprise Standard
Usage Lurasidon Hydrochloride (CAS 367514-88-3) Intermediate

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

14805-29-9 - Process Route:

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14805-29-9 - Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (3aR,4S,7R,7aS)-rel-Hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione (CAS 14805-29-9) with high quality, commercial production. It is an intermediate typically in the synthesis of Lurasidon Hydrochloride (CAS 367514-88-3) in the treatment of Schizophrenia.

Lurasidone was approved by the FDA in 2010 for schizophrenia and in 2013 for depressive episodes associated with bipolar disorder. Lurasidone is an orally administered substance that belongs to the class of atypical antipsychotic drugs (AAPD). It received approval by the EMA in 2014 for schizophrenia. Lurasidone has also been launched in a number of countries outside the US and EU, including Canada, where it is approved for both indications. It is produced through a multi-step chemical process.

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