Boc-L-Threonine CAS 2592-18-9 (Boc-Thr-OH) Purity >99.0% (HPLC) Factory

Short Description:

Chemical Name: Boc-L-Threonine

Synonyms: Boc-Thr-OH

CAS: 2592-18-9

Purity: >99.0% (HPLC)

Appearance: White Powder

Boc-Amino Acids and Derivative, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Boc-L-Threonine (Boc-Thr-OH) (CAS: 2592-18-9) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. Purchase Boc-Thr-OH, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	Boc-L-Threonine
Synonyms	Boc-Thr-OH; Boc-L-Thr-OH; N-Boc-L-Threonine; N-(tert-Butoxycarbonyl)-L-Threonine
Stock Status	In Stock
CAS Number	2592-18-9
Molecular Formula	C9H17NO5
Molecular Weight	219.24 g/mol
Melting Point	55.0~85.0℃
Density	1.202
Storage Temp.	Cool & Dry Place (0~8℃)
COA & MSDS	Available
Category	Boc-Amino Acids
Brand	Ruifu Chemical

Safety Information:

Hazard Codes	Xn	WGK Germany	3
Risk Statements	20/21/22-36/37/38	HS Code	2922491990
Safety Statements	24/25-36-26

Specifications:

Items	Inspection Standards	Results
Appearance	White Powder	White Powder
Melting Point	55.0~85.0℃	55.1~57.3℃
Specific Rotation [α]20/D	-9.0° ± 1.0° (C=2 in AcOH)	-8.4°
Water Content (K.F.)	<2.0%	1.2%
Ignition Residue (as Sulfate)	<0.20%	0.11%
Element Analysis (C、H、N)	≤5.0%	<5.0%
Boc-Thr-OH Purity	>99.0% (HPLC)	99.31%
TLC	≥98.0%	>98.0%
Clarity of Solution	0.3 gram in 2ml EtOH Clear Solution	Complies
Mass Spectrum	In Accordance With the Standard	Complies
NMR Spectrum	In Accordance With the Standard	Complies
Conclusion	This Product by Inspection Accords with the Enterprise Standard
Main Uses	Boc-Amino Acids; Peptide Synthesis; Pharmaceutical Intermediates

Package & Storage:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry (0~8℃) warehouse away from incompatible substances. Protect from light and moisture.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

Application:

Boc-L-Threonine (Boc-Thr-OH) (CAS: 2592-18-9), amino acids and derivatives, peptide synthesis, organic synthesis intermediate, pharmaceutical intermediates, biochemical reagents. Boc-L-Threonine is mainly used in polypeptide synthesis, mainly used in a variety of drugs and biotechnology applications. Threonine has a wide range of uses and functions. In the prior art, Boc is used as a protecting group to protect L-Threonine. Boc-L-Threonine is an important intermediate raw material for many kinds of medicine and biotechnology.

Preparation 1. add 15.8gL-threonine, add 200ml of 0.0005mol/L potassium bicarbonate solution, stir and dissolve, then add 8g of (Boc)2O for reaction for 2 hours, then add 8g of (Boc)2O for reaction for 2 hours, and finally add 9g of (Boc)2O for reaction for 2 hours. 2. After adjusting PH = 3 with 0.001mol/L hydrochloric acid, use tert-butyl acetate 0.4L/time to extract the product three times. Combine ester layers and wash with brine to neutral. Add 15 grams of anhydrous sodium sulfate and dry for 8 hours. 3. Filter, concentrate and dry the filtrate under reduced pressure, add 50ml petroleum ether, stir and crystallize. Centrifuge out the product and dry it. The product 22.4g is obtained. The yield is 91.73%.