7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3 Purity >99.0% (HPLC) Agomelatine Intermediate

Short Description:

Chemical Name: 7-Methoxy-1-Naphthylacetonitrile

Synonyms: 7-Methoxy-1-Naphthylmethylcyanide 

CAS: 138113-08-3

Purity: >99.0% (HPLC) 

Appearance: Light Yellow Powder

Intermediate of Agomelatine (CAS: 138112-76-2)  

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Description:

Leading Manufacturer and Supplier of Agomelatine Intermediates
Agomelatine CAS 138112-76-2
7-Methoxy-1-Tetralone CAS 6836-19-7
7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name 7-Methoxy-1-Naphthylacetonitrile 
Synonyms 7-Methoxy-1-Naphthylmethylcyanide; 7-Methoxy-1-Naphthaleneacetinitrile; 1-Cyanomethyl-7-Methoxynaphthalene; 2-(7-Methoxy-1-Naphthyl)acetonitrile; 2-(7-Methoxynaphthalen-1-yl)acetonitrile; Agomelatine Impurity 12; Agomelatine Intermediate 1 
CAS Number 138113-08-3 
CAT Number RF2504
Stock Status In Stock, Production Capacity 30 Tons per Month 
Molecular Formula C13H11NO 
Molecular Weight 197.24   
Melting Point 83.0 to 86.0℃
Density 1.135±0.06 g/cm3
Refractive Index n20/D 1.44
Solubility  Soluble in Methanol
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Light Yellow Powder 
Purity / Analysis Method >99.0% (HPLC) 
Melting Point 83.0~86.0℃
Loss on Drying <0.50%
Residue on Ignition <0.20%
Single Impurity <0.50%
Total Impurities <1.00%
Heavy Metals <20ppm
Proton NMR Spectrum Conforms to Structure
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates; Agomelatine Intermediate

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Excellent quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

7-Methoxy-1-Naphthylacetonitrile (CAS: 138113-08-3) is an intermediate of Agomelatine (CAS: 138112-76-2). Agomelatine, which is developed by the French Servier company, is the world's first melatonin receptors MT1 and MT2 agonist class of antidepressants. Agomelatine applies to the treatment of adult patients with severe depressive. Agomelatine is a new antidepressant with selective agonist actions at melatonin receptors and selective antagonist action at serotonin 5HT-2C receptors. It does not affect the uptake of serotonin, noradrenaline or dopamine. Agomelatine can help regulate your'body clock' (circadian rhythm) with positive benefits on mood and sleepin depression Agomelatine is used in the treatment of depression or to help prevent depression returning, and isonly available with a doctor's prescription. Agomelatine - Mental Illness Another "blockbuster" class of drugs. Agomelatine has antidepressant, anti-anxiety, adjusting sleep rhythm and regulating the role of the biological clock, and its adverse reactions, sexual performance without adverse effects, and no withdrawal response. Agomelatine has a good effect on patients with depression, and adverse reactions are very small. Recommended dosage for Agomelatine is generally 25mg daily within half hour before sleeping. 

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