6-Chloro-3-Methyluracil CAS 4318-56-3 Purity ≥99.0% (HPLC) Factory Alogliptin Benzoate and Trelagliptin Succinate Intermediate

Short Description:

Chemical Name: 6-Chloro-3-Methyluracil

CAS: 4318-56-3

Appearance: White to Light Yellow Powder

Purity: ≥99.0% (HPLC) 

Intermediate of Alogliptin Benzoate (CAS: 850649-62-6) and Trelagliptin Succinate (CAS: 1029877-94-8) 

Inquiry: alvin@ruifuchem.com


Product Detail

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Description:

Commercial Supply Alogliptin Benzoate (CAS: 850649-62-6) Related Intermediates:
6-Chloro-3-methyluracil CAS: 4318-56-3
2-Cyanobenzyl Bromide CAS: 22115-41-9
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS: 334618-23-4
2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h)-pyriMidinyl)Methyl]benzonitrile CAS: 865758-96-9

Commercial Supply Trelagliptin Succinate (CAS: 1029877-94-8) Related Intermediates: 
6-Chloro-3-Methyluracil CAS: 4318-56-3
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS: 334618-23-4
2-Cyano-5-Flurobenzyl Bromide CAS: 421552-12-7

Chemical Properties:

Chemical Name 6-Chloro-3-Methyluracil
CAS Number 4318-56-3
CAT Number RF-PI141
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C5H5ClN2O2
Molecular Weight 160.56
Melting Point 278.0~280.0℃
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Light Yellow Powder
Identification HPLC: The retention time of the major peak in chromatograms corresponds to that in the reference standard
Purity / Analysis Method ≥99.0% (HPLC)
Max Single Impurity ≤0.50%  (HPLC)
Total Impurities ≤0.50%  (HPLC)
Moisture (K.F) ≤0.50%
Loss on Drying ≤1.0%
Residue on Ignition ≤0.10%
Test Standard Enterprise Standard
Usage Alogliptin Benzoate, Trelagliptin Succinate Intermediate 

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

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FAQ:

2

Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 6-Chloro-3-methyluracil  (CAS: 4318-56-3) with high quality, widely used in organic synthesis, synthesis of pharmaceutical intermediates and active pharmaceutical ingredient (API) synthesis.

6-Chloro-3-methyluracil (CAS: 4318-56-3) is used in the synthesis of Alogliptin Benzoate (CAS: 850649-62-6) and Trelagliptin Succinate (CAS: 1029877-94-8). 

Alogliptin Benzoate (CAS: 850649-62-6)  is a type-2 diabetes medication, and it is a type of serine protease dipeptidyl peptidase IV (DPP-4) inhibitor developed by the Japanese company Takeda. Alogliptin, used alone or in combination with other blood sugar-lowering medication, is usually well-tolerated in type-2 diabetes patients.  

Trelagliptin Succinate (CAS: 1029877-94-8) (SYR-472) is a selective, long acting dipeptidyl peptidase-4 (DPP-4) inhibitor. An antidiabetic agent. Orally active DPP-4 inhibitor that produces clinically and statistically significant improvements in glycaemic control in patients with type 2 diabetes.  

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