5-Methylisatin CAS 608-05-9 Purity >98.0% (HPLC)

Short Description:

Chemical Name: 5-Methylisatin

Synonyms: 5-Methylindole-2,3-Dione

CAS: 608-05-9

Purity: >98.0% (HPLC)

Appearance: Orange to Red Powder

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 5-Methylisatin (CAS: 608-05-9) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 5-Methylisatin, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	5-Methylisatin
Synonyms	5-Methylindole-2,3-Dione; 5-Methyl-2,3-Indolinedione
Stock Status	In Stock, Commercial Production
CAS Number	608-05-9
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Melting Point	186.0 to 190.0℃
Density	1.301±0.06 g/cm3
COA & MSDS	Available
Sample	Available
Origin	Shanghai, China
Brand	Ruifu Chemical

Specifications:

Items	Inspection Standards	Results
Appearance	Orange to Red Powder	Complies
Melting Point	186.0 to 190.0℃	186.0 to 190.0℃
Water by Karl Fischer	<0.50%	0.33%
Single Impurity	<1.00%	0.41%
Total Impurities	<2.00%	0.85%
Purity / Analysis Method	>98.0% (HPLC)	99.15%
1H NMR Spectrum	Consistent with Structure	Complies
Conclusion	The product has been tested and complies with the given specifications

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

608-05-9 - HPLC Method:

HPLC Method for 5-Methylisatin (CAS: 608-05-9)
Instrument:
HP 1100 Agilent
or
Dionex, Summit
Settings:
Column: Nucleosil 100-5 C18 HD by Macherey Nagel Item No.: 721850.40
Length: 250mm
Inner Diameter: 4.0mm
Flow: 1ml/mim
Detection: 220nm
Injection Volume: 30μL
Typ: Gradient
Run Time: 38min + equlibrate for 12 minutes
Reagents:
Water HPLC quality
Acetonitrile HPLC quality
Potassium dihydrogenphosphate p.a.
Phosphoric acid 85%, p.a.
Buffer-solution pH3.0:
Dissolve 2.72g Potassium dihydrogenphosphate in 1000ml Water and adjust the pH to 3.0 with Phosphoric acid. Then filter through Millipore membrane filter (Item No.: HVLP04700, 0.45μm).
Eluent A: Buffer-solution pH 3.0 : Acetonitrile = 19 : 1
Eluent B: Buffer-solution pH 3.0 : Acetonitrile = 3 : 7
Run Time A : B
0 min 100 : 0
Within 28 min 0 : 100
10 min 0 : 100
Aquisition off
Within 11 min 100 : 0
39-50 min. 100 : 0 equlilibrate
Solvent: Water : ACN = 4 : 1
Test Solution:
Dissolve approx. 100mg sample, exactly weighted, in 25ml Acetonitrile and sonicate. Dilute 1ml of this solution to 20ml with solvent and filter through 0.45μm.
Injection sequence:
1 x Blank
2 x Test solution
Calculation:
Area percent.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

608-05-9 - Safety Information:

Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
RTECS NL7939300
Hazard Class IRRITANT

608-05-9 - Application:

5-Methylisatin (CAS: 608-05-9) may be used as an organic intermediate; A dye intermediate; A biological stain, etc.
Reactant for preparation of:
Antimycobacterial agents
Promoters of central nervous system (CNS) depression in mice
Inhibitors of TAK1 kinase
Anti-human immunodeficiency virus (HIV) agent
Potent herpes simplex virus (HSV) inhibitors
Antimicrobial agents
IKKβ inhibitors
Potential drug to combat human immunodeficiency virus-tuberculosis (HIV-TB) coinfection
Cyclooxygenase 1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) inhibitors
Antibacterial and anticancer agents