4-Methylpyrazole (Fomepizole) CAS 7554-65-6 Purity >98.5% (GC) Factory

Short Description:

Chemical Name: 4-Methylpyrazole

Synonyms: 4-Methyl-1H-Pyrazole; Fomepizole

CAS: 7554-65-6

Purity: >98.5% (GC)  

Appearance: Colorless or White to Yellow Liquid or Solid

High Quality, Commercial Production

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E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 4-Methylpyrazole (Fomepizole) (CAS: 7554-65-6) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name 4-Methylpyrazole  
Synonyms 4-Methyl-1H-Pyrazole; 4-Methyl-Pyrazol; Fomepizole; Antizol; 4-MP 
CAS Number 7554-65-6 
CAT Number RF2598
Stock Status In Stock, Production Capacity 30 Tons per Month
Molecular Formula C4H6N2  
Molecular Weight 82.11  
Melting Point 13℃
Boiling Point 99.0~100.0℃/6 mm Hg(lit.)
Density 0.993 g/mL at 25℃(lit.)
Refractive Index n20/D 1.492~1.498 (lit.)
Sensitive Hygroscopic. Air Sensitive 
Water Solubility  Miscible With Water, Ether, Benzene and Alcohol  
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Colorless or White to Yellow Liquid or Solid (Liquid After Melting)
Purity / Analysis Method >98.5% (GC)  
Moisture (K.F) <0.50%
Total Impurities <1.50%
Infrared Spectrum Conforms to Structure
Proton NMR Spectrum Conforms to Structure
Test Standard Enterprise Standard
Note Low Melting Point, May Change State in Different Environments (Solid, Liquid or Semi-Solid)
Usage Pharmaceutical Intermediates

Package & Storage:

Package: Fluorinated Bottle, 25kg/Barrel, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Excellent quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

4-Methylpyrazole (Fomepizole) (CAS: 7554-65-6) is a compound of heterocyclic building blocks, it serves as an intermediate in organic synthesis, also used as a pharmaceutical intermediate. It acts a ligand in coordination chemistry. Fomepizole was approved by the U.S. Food and Drug Administration (FDA) on Dec 4, 1997. Fomepizole is the first drug indicated as an antidote for ethylene glycol poisoning. It was developed and marketed as Antizol® by Paladin in the US. Fomepizole is a competitive alcohol dehydrogenase inhibitor, Alcohol dehydrogenase catalyzes the oxidation of ethanol to acetaldehyde, and it also catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites. Antizol® is indicated as an antidote for ethylene glycol (such as antifreeze) or methanol poisoning, or for use in suspected ethylene glycol or methanol ingestion, either alone or in combination with hemodialysis. Fomepizole is a competitive antagonist of alcohol dehydrogenase with a binding affinity >8000 times that of Ethanol. 

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