2(5H)-Furanone CAS 497-23-4 Purity >95.0% (GC)

Short Description:

Chemical Name: 2(5H)-Furanone

Synonyms: γ-Crotonolactone 

CAS: 497-23-4

Purity: >95.0% (GC)

Appearance: Colorless to Light Yellow Liquid 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 2(5H)-Furanone (γ-Crotonolactone) (CAS: 497-23-4) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 2(5H)-Furanone, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name 2(5H)-Furanone  
Synonyms γ-Crotonolactone; gamma-Crotonolactone; 2-Oxo-2,5-Dihydrofuran; 2-Buten-1,4-olide; 2H-Furan-5-one; γ-Hydroxycrotonic Acid Lactone
Stock Status In Stock, Commercial Production 
CAS Number 497-23-4
Molecular Formula C4H4O2
Molecular Weight 84.07 g/mol
Melting Point 4.0~5.0℃(lit.) 
Boiling Point 212.0~214.0℃
Flash Point 101℃(213°F)
Density 1.185 g/mL at 25℃(lit.) 
Refractive Index n20/D 1.469(lit.)
Sensitive Light, Air Sensitive, Heat, Moisture Sensitive
Water Solubility  Immiscible with Water 
COA & MSDS Available
Origin Shanghai, China
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance Colorless to Light Yellow Liquid
Light Yellow Liquid 
Water by Karl Fischer  <0.50% 0.1% 
Purity / Analysis Method >95.0% (GC)  97.9% 
Refractive Index n20/D 1.468~1.472 Complies 
Density (20℃) 1.185~1.202   Complies   
Infrared Spectrum Consistent with Structure Complies 
1 H NMR Spectrum  Consistent with Structure Complies
Conclusion The product has been tested & complies with the given specifications

Package/Storage/Shipping:

Package: Bottle, 25kg/Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

497-23-4 Safety Information:

Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
RTECS LU3453000
FLUKA BRAND F CODES 8-10
Hazard Note Irritant

497-23-4 Application:

2(5H)-Furanone (γ-Crotonolactone) (CAS: 497-23-4) is a heterocyclic organic compound that is used widely in the synthetic preparation of pharmaceutical products.
2(5H)-Furanone is the simplest crotonolactone, its structural formula is γ-crotonyl lactone, which is a precursor material of many active molecules of drugs, and its structure is commonly found in bioactive molecules, such as antibiotics, antibiotics, anti-tumor and antiviral drugs.
2(5H)-Furanone is employed in the preparation of 5-substituted 2(5H) furanones (gamma-butenolides) catalyzed by bifunctional aminothiourea and aminosquaramide organocatalysts through direct aldol reaction with aromatic aldehydes. Further, it is used in the synthesis of lignans by Michael addition reactions. In addition to this, it is used in three-component Michael-Aldol reactions with an aldehyde and thiolate or carbanion.
Biological activity: 2(5H)-Furanone is an endogenous metabolite. 

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