(1S,2R)-(-)-1-Amino-2-indanol CAS 126456-43-7 Purity ≥99.0% E.E. ≥99.0% Indinavir Sulfate Intermediate

Short Description:

Chemical Name: (1S,2R)-(-)-1-Amino-2-indanol

CAS: 126456-43-7

Appearance: White to Pale Yellow Powder

Purity: ≥99.0%  E.E.: ≥99.0%

Intermediate of Indinavir Sulfate (CAS: 157810-81-6) in the treatment of HIV Infection and AIDS

Inquiry: alvin@ruifuchem.com


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Description:

Manufacturer with High Quality and Competitive Price
Commercial Supply Indinavir Sulfate (CAS: 157810-81-6) Related Intermediates:
(1R,2S)-(+)-1-Amino-2-indanol CAS: 136030-00-7
(1S,2R)-(-)-1-Amino-2-indanol CAS: 126456-43-7

Chemical Properties:

Chemical Name (1S,2R)-(-)-1-Amino-2-indanol
Synonyms (1S,2R)-(-)-1-Amino-2-hydroxyindan
CAS Number 126456-43-7
CAT Number RF-CC120
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C9H11NO
Molecular Weight 149.19
Solubility (Soluble in) Methanol
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Pale Yellow Powder  
Specific Rotation [α]D20 -47.0°~ -42.0° (C=1,MeOH)
Melting Point 115.0~121.0℃
Purity / Analysis Method ≥99.0% (HPLC)
Loss on Drying ≤0.50%
Moisture (K.F) ≤0.50%
E.E ≥99.0%
Test Standard Enterprise Standard
Usage Indinavir Sulfate (CAS: 157810-81-6) Intermediates 

Package & Storage:

Package: Bottle, Cardboard Drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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FAQ:

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Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (1S,2R)-(-)-1-Amino-2-indanol (CAS: 126456-43-7) with high quality. (1S,2R)-(-)-1-Amino-2-indanol (CAS: 126456-43-7) is an intermediate typically in the synthesis of Indinavir Sulfate (CAS: 157810-81-6).  

Indinavir Sulfate (CAS: 157810-81-6) (MK-639) is a protease inhibitor used as a component of highly active antiretroviral therapy (HAART) to treat HIV infection and AIDS. MK-639 appears to have significant dose-related antiviral activity and is well tolerated. Indinavir is a potent inhibitor of HIV reverse transcriptase. It produces the side effects common to all protease inhibitors and also may produce nephrolithiasis, urolithiasis, and possibly renal insufficiency or renal failure. This problem occurs more frequently in children (approximately 30%) than adults (approximately 10%) and can be minimized by drinking at least 1.5 L of water daily. Additional side effects include asymptomatic hyperbilirubinemia, alopecia, ingrown toenails, and paronychia. Hemolytic anemia rarely occurs. Rifampin should not be given with indinavir.

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