1-Bromo-2-Butyne CAS 3355-28-0 Purity ≥99.0% (GC) Linagliptin Intermediate Factory

Short Description:

Chemical Name: 1-Bromo-2-Butyne

CAS: 3355-28-0

Purity: ≥99.0% (GC)

Appearance: Colorless to Slight Yellow Liquid

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

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3355-28-0 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 1-Bromo-2-Butyne (CAS: 3355-28-0) with high and stable quality control, intermediate of Linagliptin (CAS: 668270-12-0).
Ruifu Chemical has been supplying pharmaceutical intermediates and APIs, fine chemicals more than 15 years. Our products are well received by domestic and foreign pharmaceutical companies and R&D institutions.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service. Purchase 1-Bromo-2-Butyne and Linagliptin intermediates or other products, please contact us by e-mail: alvin@ruifuchem.com

Intermediates of Linagliptin:

Manufacturer Supply Linagliptin and Related Intermediates:
Linagliptin CAS 668270-12-0
Linagliptin Parent Nucleus Intermediate CAS 853029-57-9
8-Bromo-3-Methylxanthine CAS 93703-24-3
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine CAS 666816-98-4
2-(Chloromethyl)-4-Methylquinazoline CAS 109113-72-6
(R)-3-(Boc-Amino)piperidine CAS 309956-78-3
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
1-Bromo-2-Butyne CAS 3355-28-0

3355-28-0 - Chemical Properties:

Chemical Name	1-Bromo-2-Butyne
Synonyms	2-Butynyl Bromide; 1-Bromobut-2-yne
CAS Number	3355-28-0
Stock Status	In Stock, Commercial Production
Molecular Formula	C4H5Br
Molecular Weight	132.99
Boiling Point	40.0~41.0℃/20 mmHg (lit.)
Density	1.519 g/ml at 25℃ (lit.)
Refractive Index n20/D	1.508(lit.)
Solubility	Miscible with Acetonitrile
Sensitive	Air Sensitive. Store Under Inert Gas
COA & MSDS	Available
Origin of Product	Shanghai, China
Product Categories	Pharmaceutical Intermediates
Brand	Ruifu Chemical

3355-28-0 - Specifications:

Item	Specifications	Results
Appearance	Colorless to Slight Yellow Liquid	Slight Yellow Liquid
1-Bromo-2-Butyne Purity	≥99.0% (GC)	99.8%
Moisture (K.F)	≤0.20%	0.09%
Refractive Index n20/D	1.507~1.509	Conforms
Single Impurity	≤0.30%	0.06%
Total Impurities	≤1.00%	0.20%
Infrared Spectrum	Conforms to Structure	Conforms to Structure
Remarks	The color will get darker after exposed to air frequently
	Store in low-temperature, dark, dry and nitrogen-protected place
	Use it out as soon as possible after opening
Conclusion	The product has been tested and complies with the given specifications

3355-28-0 - Package/Storage/Shipping:

Package: Bottle, 25kg/drum or 220kg Plastic drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry, well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.

3355-28-0 - Advantages:

3355-28-0 - FAQ:

3355-28-0 - Risk and Safety:

Risk Codes 10 - Flammable
Safety Description S16 - Keep away from sources of ignition.
S24/25 - Avoid contact with skin and eyes.
UN IDs UN 1993 3/PG 3
WGK Germany 3
FLUKA BRAND F CODES 10-23
HS Code 2934999099
Hazard Class 3
Packing Group III

3355-28-0 - Application:

1-Bromo-2-Butyne (CAS: 3355-28-0) is a chemical compound that belongs to the group of alkynes, which are hydrocarbons that contain at least one triple bond between two carbon atoms. 1-Bromo-2-Butyne is a highly reactive organic compound that has been widely used in organic synthesis, synthesis of pharmaceutical intermediates and Active Pharmaceutical Ingredient (API) synthesis.
1-Bromo-2-Butyne is a key intermediate in the synthesis of Linagliptin (CAS: 668270-12-0) for the treatment of adults with type 2 diabetes mellitus.
1-Bromo-2-Butyne has been used in a wide range of scientific research applications. It has been used as a reagent in organic synthesis, as a catalyst in polymerization reactions, and as a reagent in catalytic transformations. It has also been used in the synthesis of pharmaceuticals, and other materials.