Reliable Supplier Enalapril Maleate - Betamethasone CAS 378-44-9 Purity 97.0%~103.0% API High Purity – Ruifu
Reliable Supplier Enalapril Maleate - Betamethasone CAS 378-44-9 Purity 97.0%~103.0% API High Purity – RuifuDetail:
Commercial Supply Betamethasone with High Purity and Stable Quality
Chemical Name: Betamethasone
CAS: 378-44-9
Appearance: White or Almost White Crystalline Powder
Purity: 97.0%~103.0% of C22H29FO5 calculated on the dried basis
Loss on Drying: ≤0.50%
| Chemical Name | Betamethasone |
| CAS Number | 378-44-9 |
| CAT Number | RF-API12 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C22H29FO5 |
| Molecular Weight | 392.47 |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White or Almost White Crystalline Powder |
| Identification | Complies by IR, TLC |
| Specific Optical Rotation | +118° to +126° (calculated on the dried basis) |
| Individual Impurity | ≤1.0% |
| Total Impurities | ≤2.0% |
| Residual Solvents Methanol | ≤3000ppm |
| Residual Solvents Chloroform | ≤60ppm |
| Loss on Drying | ≤0.50% (Dry it at 105℃, 3 hours) |
| Residue on Ignition | ≤0.20% |
| Purity | 97.0%~103.0% of C22H29FO5 calculated on the dried basis |
| Test Standard | Chinese Pharmacopoeia (CP); EP10.0 and USP 42 |
| Packaging and Storage | Preserve in tight containers. Store between 2℃ and 30℃ . |
| Usage | Active Pharmaceutical Ingredient (API) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Betamethasone, belongs to adrenal corticosteroids, it is a isomer of dexamethasone , and the role of betamethasone is similiar to prednisolone and dexamethasone , it has anti-inflammatory, anti-rheumatic, anti-allergic and suppression of the immune and other pharmacological effects, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone etc. , it can reduce and prevent tissue response to inflammation and eliminate heat, redness and swelling caused by local non-infectious inflammation, thereby reducing the performance of inflammation, anti-inflammatory effect of this product 0.3mg is equal to dexamethasone 0.75mg, prednisone 5mg or 25mg cortisone . Betamethasone sodium retention effect is a hundred times more than hydrocortisone, in primary adrenal hypofunction, it can be used together with glucocorticoid for replacement therapy ,and it is used for preventing or inhibiting cell-mediated immune response, delaying allergic reactions and reducing the primary immune response expansion ,it is used for low renin and low aldosterone syndrome and autonomic neuropathy induced orthostatic hypotension. Currently betamethasone is also used for the treatment of active rheumatoid arthritis, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, atopic dermatitis, eczema, neurodermatitis, seborrheic dermatitis, and pruritus and comprehensive treatment of certain infections. The product is contraindicated in severe psychiatric history, active duodenal ulcer, recent gastrointestinal anastomosis, heavier osteoporosis, overt diabetes, severe hypertension, virus , bacterial, fungal infections which are failed to control by the use of antimicrobial agents , thrombophlebitis, skin infections, such as impetigo, tinea, jock itch and so on.
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