High Quality (S)-(+)-3-Hydroxytetrahydrofuran - Boc-Leu-OH.H2O CAS 13139-15-6 Purity ≥98.5% (HPLC) – Ruifu

Short Description:

Product Detail

Product Tags

Feedback (2)

We normally think and practice corresponding on the change of circumstance, and grow up. We aim at the achievement of a richer mind and body and also the living for CAS 13505-32-3, p-Aminobenzamide glutamic acid, Ambrisentan Intermediate, It is our great honor to meet your demands.We sincerely hope we can cooperate with you in the near future.

High Quality (S)-(+)-3-Hydroxytetrahydrofuran - Boc-Leu-OH.H2O CAS 13139-15-6 Purity ≥98.5% (HPLC) – Ruifu Detail:

Manufacturer Supply; High Purity and Competitive Price
Shanghai Ruifu Chemical Co., Ltd. Commercial Supply Carfilzomib (CAS: 868540-17-4) Related Intermediates:
Boc-L-Leucine.H2O;Boc-L-Leucine monohydrate; CAS: 13139-15-6
Boc-L-Homophenylalanine; Boc-L-HomePhe-OH; CAS: 100564-78-1
2-Bromopropene CAS: 557-93-7

Chemical Name	Boc-Leu-OH.H2O
Synonyms	Boc-L-Leucine.H2O; Boc-L-Leu-OH; Boc-L-Leucine Monohydrate
CAS Number	13139-15-6
CAT Number	RF-PI115
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C11H21NO4
Molecular Weight	231.29
Density	1.061±0.06 g/cm3
Boiling Point	356℃ at 760 mmHg
Brand	Ruifu Chemical

Item	Specifications
Appearance	White or Off-White Crystalline Powder
Specific Rotation	-23.0° ~ -26.0° (C=1, AcOH)
Purity / Analysis Method	≥98.0% (HPLC)
Melting Point	82.0 ~ 90.0℃
Test Standard	Enterprise Standard
Usage	Pharmaceutical Intermediates; Organic Synthesis

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

121

Shanghai Ruifu Chemical Co., Ltd. Commercial Supply Carfilzomib (CAS: 868540-17-4) Related Intermediates:
Boc-L-Leucine.H2O;Boc-L-Leucine monohydrate; CAS: 13139-15-6
Boc-L-Homophenylalanine; Boc-L-HomePhe-OH; CAS: 100564-78-1
2-Bromopropene CAS: 557-93-7

Carfilzomib is an irreversible proteasome inhibitor and antineoplastic agent.The mechanism of action of carfilzomib is as a Proteasome Inhibitor, Carfilzomib irreversibly binds to and inhibits the chymotrypsin-like activity of the 20S catalytic core subunit of the proteasome, a protease complex responsible for degrading a large variety of cellular proteins. Inhibition of proteasome-mediated proteolysis results in an accumulation of polyubiquinated proteins, which may lead to cell cycle arrest, induction of apoptosis, and inhibition of tumor growth.
Carfilzomib is used in treatment of refractory multiple myeloma. Carfilzomib is associated with a low rate of serum enzyme elevations during treatment and has been implicated to rare instances of clinically apparent, acute liver injury some of which have been fatal.
Carfilzomib is a second-generation, irreversible, peptide epoxyketone class proteasome inhibitor that targets the chymotrypsin-like β5 subunit of the constitutive 20S proteasome (IC50 = 5.2 nM) and the β5i subunit of the immunoproteasome 20Si (LMP7; IC50 = 14 nM) with minimal cross reactivity to other proteases. It can induce cell cycle arrest and apoptosis in human cancer cell lines including multiple myeloma, lymphoma, and various solid tumors

Product detail pictures:

Related Product Guide:

High quality Very first,and Consumer Supreme is our guideline to offer the most beneficial service to our consumers.At present, we're attempting our greatest to be among the top exporters in our area to fulfill buyers far more need to have for High Quality (S)-(+)-3-Hydroxytetrahydrofuran - Boc-Leu-OH.H2O CAS 13139-15-6 Purity ≥98.5% (HPLC) – Ruifu , The product will supply to all over the world, such as: Bahamas, Johor, Luxembourg, Furthermore, all of our products are manufactured with advanced equipment and strict QC procedures in order to ensure high quality. If you are interested in any of our products, please don't hesitate to contact us. We will do our best to meet your needs.