H-Tyr-OEt·HCl CAS 4089-07-0 L-Tyrosine Ethyl Ester Hydrochloride Purity >99.0% (HPLC) Factory

Short Description:

L-Tyrosine Ethyl Ester Hydrochloride

Synonyms: H-Tyr-OEt·HCl 

CAS: 4089-07-0 

Purity: >99.0% (HPLC) 

Appearance: White to Off-White Powder  

Amino Acids Derivatives, High Quality 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of L-Tyrosine Ethyl Ester Hydrochloride (H-Tyr-OEt·HCl) (CAS: 4089-07-0). Ruifu Chemical supplys amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. Purchase H-Tyr-OEt·HCl, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name L-Tyrosine Ethyl Ester Hydrochloride 
Synonyms H-Tyr-OEt·HCl; L-Tyr-OEt·HCl; Ethyl L-Tyrosinate Hydrochloride; Ethyl 2-Amino-3-(4-Hydroxyphenyl)propanoate Hydrochloride
Stock Status In Stock, Production Capacity 20 Tons per Month 
CAS Number 4089-07-0 
Molecular Formula C11H15NO3·HCl
Molecular Weight 245.70 g/mol
Melting Point 165.0~170.0℃ 
Density 1.177 
Sensitive Air Sensitive, Heat Sensitive  
Solubility in Water   Almost Transparency  
Storage Temp.  Cool & Dry Place (0~8℃) 
COA & MSDS Available
Category   Amino Acids Derivatives 
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance White to Off-White Powder  White Powder 
Specific Rotation [α]20/D -6.3° to -7.3° (C=2 in H2O)
-6.5°
Melting Point 165.0~170.0℃ 166.0~167.0℃
Loss on Drying <0.50% 0.22% 
Residue on Ignition <0.10% 0.07%
Heavy Metals (Pb) ≤10ppm <10ppm 
Arsenic (As) ≤1ppm <1ppm 
Purity / Analysis Method >99.0% (HPLC)  99.5% 
Infrared Spectrum Conforms to Structure Complies      
NMR Spectrum Conforms to Structure Complies      
Conclusion This Product by Inspection Accords with the Enterprise Standard

Package & Storage:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry (0~8℃) warehouse away from incompatible substances. Protect from light and moisture.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

4089-07-0 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 2
RTECS YP2580000
HS Code 2922491990

Application:

L-Tyrosine Ethyl Ester Hydrochloride (H-Tyr-OEt·HCl) (CAS: 4089-07-0) is used as a medical and organic intermediate and as an important amino protective agent. It is also used to introduce t-Boc protect gene. Amino acids derivatives, used in peptide synthesis, organic synthesis intermediates, pharmaceutical intermediates, biochemical reagents, chemical reagents. 
Introduction: L-Tyrosine is one of the 20 amino acids that make up proteins and is an essential amino acid for mammals. L-Tyrosine Ethyl Ester Hydrochloride is the main raw material for the synthesis of a variety of peptide hormones, antibiotics and other drugs.
Use: L-Tyrosine Ethyl Ester Hydrochloride is the main raw material for synthesizing a variety of peptide hormones, antibiotics and other drugs. In the food industry, L-Tyrosine Ethyl Ester Hydrochloride is used instead of amino acids as food additives, which can change the taste and flavor of food and increase the shelf life of food. Amino acid esters used in food also increase the solubility of amino acids and the specificity of enzyme catalysis, which is beneficial to the digestion and absorption of the body and plays a dual role in nutrition and health care.
Preparation method: Add 19 mL of anhydrous ethanol into a 250 mL three-mouth flask equipped with a stirrer, a dropping funnel and a thermometer, cool it to about -8℃ in an ice salt bath for external use, slowly add 2.4 mL of sulfoxide chloride under stirring (the dropping acceleration is limited to the reaction temperature not exceeding 0℃), after dropping, stir at this temperature for 1 h, add 4.5g L-Tyrosine under cooling conditions, raise the temperature to room temperature and stir for 2 h, then heat and reflux at 65℃ for 2 h, distill after the reaction to evaporate most methanol and excess thionyl chloride, transfer the residue to a beaker for cooling, add 125 mL ethyl acetate to precipitate a large amount of crystals, vacuum filtration, and collect crystals, L-Tyrosine Ethyl Ester Hydrochloride was obtained.  

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