Good quality 6-Fluoro-3-Hydroxy-2-Pyrazinecarboxamide - Ezetimibe CAS 163222-33-1 Purity 98.5%~102.0% (HPLC) API High Purity – Ruifu

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Good quality 6-Fluoro-3-Hydroxy-2-Pyrazinecarboxamide - Ezetimibe CAS 163222-33-1 Purity 98.5%~102.0% (HPLC) API High Purity – Ruifu Detail:

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Commercial Supply Ezetimibe (CAS: 163222-33-1) Related Intermediates:
(S)-(+)-4-Phenyl-2-oxazolidinone CAS: 99395-88-7
(R)-(+)-2-Methyl-CBS-oxazaborolidine CAS: 112022-83-0
4-(4-Fluorobenzoyl)butyric acid CAS: 149437-76-3
4-[[(4-Fluorophenyl)imino]methyl]-phenol CAS: 3382-63-6
N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline CAS: 70627-52-0
(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one CAS 190595-65-4
(4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone CAS: 189028-93-1
(4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one CAS: 189028-95-3
Ezetimibe CAS: 163222-33-1

Chemical Name	(3R,4S)-1-(4-Fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
Synonyms	Ezetimibe
CAS Number	163222-33-1
CAT Number	RF-API02
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C24H21F2NO3
Molecular Weight	409.43
Melting Point	162.0 ~ 166.0℃
Brand	Ruifu Chemical

Item	Specifications
Appearance	White to Off-White Powder
Purity / Analysis Method	98.5%~102.0% (HPLC)
Specific Rotation	-25.0°~ -30.0°
Moisture (K.F)	≤0.50%
Heavy Metals	≤0.002%
Enantiomer	≤0.30%
Single Max. Impurity	≤0.50%
Total Impurities	≤1.0%
Test Standard	Enterprise Standard
Usage	Ezetimibe (CAS: 163222-33-1) API

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Ezetimibe (CAS: 163222-33-1) is a cholesterol transport inhibitor that binds to NPC1L1, belongs to a class of substances used to lower cholesterol levels in the blood is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone when other cholesterol-lowering medications are not tolerated, or together with statins (e.g., ezetimibe/simvastatin) when statins alone do not control cholesterol. Ezetimibe is orally administered alone or as a combination tablet with either simvastatin or atorvastatin. Ezetimibe was approved in 2002 by the FDA, under the trade name Zetia. It is approved for use in the EU as Ezetrol and other trade names. It is produced through a multi-step chemical process.

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