Factory directly supply Ribofuranose - 5-Hydroxymethylcytosine 5-HmC CAS 1123-95-1 Purity ≥98.0% (HPLC) – Ruifu
Factory directly supply Ribofuranose - 5-Hydroxymethylcytosine 5-HmC CAS 1123-95-1 Purity ≥98.0% (HPLC) – Ruifu Detail:
Manufacturer with High Purity and Stable Quality
Name | 5-Hydroxymethylcytosine |
Synonyms | 5-HmC |
CAS Number | 1123-95-1 |
CAT Number | RF-PI182 |
Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
Molecular Formula | C5H7N3O2 |
Molecular Weight | 141.13 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White or Off-White Powder |
Purity / Analysis Method | ≥98.0% (HPLC) |
Loss on Drying | ≤0.50% |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Intermediates; Organic Synthesis |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
5-Hydroxymethylcytosine (5hmC) (CAS: 1123-95-1) is a DNA pyrimidine nitrogen base derived from cytosine. It is potentially important in epigenetics, because the hydroxymethyl group on the cytosine can possibly switch a gene on and off. It was first seen in bacteriophages in 1952.[1][2] However, in 2009 it was found to be abundant in human and mouse brains,[3] as well as in embryonic stem cells.[4] In mammals, it can be generated by oxidation of 5-methylcytosine, a reaction mediated by TET enzymes. Its molecular formula is C5H7N3O2. It may regulate gene expression or prompt DNA demethylation. 5-Hydroxymethylcytosine (CAS: 1123-95-1) may be especially important in the central nervous system, as it is found in very high levels there. 5-Hydroxymethylcytosine (5hmC) is a naturally existing component in mammalian genomic DNA and is regarded as the sixth DNA base. 5-Hydroxymethylcytosine (CAS: 1123-95-1) is an intermediate metabolite in active DNA demethylation.
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