China Factory for 2-Phenylethylamine - 7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity – Ruifu
China Factory for 2-Phenylethylamine - 7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity – Ruifu Detail:
Manufacturer with High Purity and Stable Quality
Supply Irinotecan and Related Intermediates:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Chemical Name | 7-Ethyl-10-Hydroxycamptothecin |
| Synonyms | SN-38 |
| CAS Number | 86639-52-3 |
| CAT Number | RF-PI242 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C22H20N2O5 |
| Molecular Weight | 392.41 |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | Light Yellowish White Crystals Powder |
| Identification (IR, UV) | (1) Ultraviolet ray absorption spectrum accord with the demands (2) Infrared ray absorption spectrum concordant with reference standard spectrum shall comply with approved tests |
| Melting Point | 228.0~235.0℃ |
| Related Substances | ≤1.5% |
| 10-Hydroxycamptothecin | ≤0.30% |
| 7-Cthylcamptothecin | ≤0.70% |
| Maximum Unknown Impurity | ≤0.50% |
| Loss on Drying | ≤1.0% |
| Heavy Metals | ≤10ppm |
| Residue on Ignition | ≤0.10% |
| Clarity of Solution | Clear |
| Assay | ≥98.0% (HPLC) |
| Test Standard | Enterprise Standard |
| Usage | Pharmaceutical Intermediate of Irinotecan |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) with high quality. 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. 7-Ethyl-10-Hydroxycamptothecin (SN-38), is the active metabolite of Irinotecan, a semisynthetic derivative of camptothecin, a quinoline-based alkaloid found in the bark of the Chinese camptotheca tree and the Asian nothapodytes tree. Although 7-Ethyl-10-Hydroxycamptothecin is up to 1,000 times more potent than Irinotecan, it has not been converted into a viable drug candidate because it is insoluble. It is presently being subjected to clinical trials in combination with other moieties which may ultimately allow it to be efficacious as an antineoplastic drug.
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Our growth depends on the superior equipment ,exceptional talents and continuously strengthened technology forces for China Factory for 2-Phenylethylamine - 7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity – Ruifu , The product will supply to all over the world, such as: Istanbul, Swedish, Israel, Our advantages are our innovation, flexibility and reliability which have been built during last 20 years. We focus on providing service for our clients as a key element in strengthening our long-term relationships. The continual availability of high grade products in combination with our excellent pre- and after-sales service ensures strong competitiveness in an increasingly globalized market.
By Maxine from Lyon - 2018.06.19 10:42
After the signing of the contract, we received satisfactory goods in a short term, this is a commendable manufacturer.
By Christian from Czech - 2017.12.09 14:01