2021 New Style Ropivacaine Hydrochloride Monohydrate - Bortezomib CAS 179324-69-7 Purity ≥99.0% (HPLC) API Factory High Purity – Ruifu

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2021 New Style Ropivacaine Hydrochloride Monohydrate - Bortezomib CAS 179324-69-7 Purity ≥99.0% (HPLC) API Factory High Purity – Ruifu Detail:

Supply Bortezomib Related Intermediates with High Purity
(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8
(1R,2R,3S,5R)-(-)-2,3-Pinanediol CAS 22422-34-0
Bortezomib CAS 179324-69-7

Chemical Name	Bortezomib
Synonyms	Velcade, MG-341, PS-341
CAS Number	179324-69-7
CAT Number	RF-API65
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C19H25BN4O4
Molecular Weight	384.24
Melting Point	122.0~124.0℃
Density	1.214
Refractive Index	1.564
Solubility	Soluble in Chloroform, DMSO, Ethanol and Methanol
Stability	Hygroscopic and Moisture Sensitive
Shipping Condition	Shipped Under Ambient Temperature
Brand	Ruifu Chemical

Item	Specifications
Appearance	White or Off-White Powder
Purity / Analysis Method	≥99.0% (HPLC)
Loss on Drying	≤0.50%
Residue on Ignition	≤0.20%
Optical Rotation	-41.0° ~ -46.0°
Heavy Metal	≤20ppm
Acidity	4.0~7.0
Isomer	≤0.50%
Single Impurity	≤0.50%
Total Impurities	≤1.0%
Residual Solvents
Methanol	≤0.30%
Dichloromethane	≤0.05%
Hexane	≤0.02%
Ethyl Acetate	≤0.50%
Test Standard	Enterprise Standard
Usage	API

Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Bortezomib (CAS: 179324-69-7) with high quality, API.

Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. Bortezomib was approved for medical use in the United States in 2003 and in the European Union in 2004. It is on the World Health Organization’s List of Essential Medicines. Bortezomib is the first proteasome inhibitor to be approved b the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Bortezomib is a selective and robust 26S proteasome inhibitor, that is a boronic acid dipeptide derivative. Human pancreatic cancer cell studies demonstrate Bortezomib to inhibit the PKR-like endoplasmic reticulum (ER) kinase and enhance ER stress, leading to apoptosis.

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