2021 High quality (R)-(+)-4-Methoxy-α-methylbenzylamine - (S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2 Afatinib Amprenavir Fosamprenavir Intermediate – Ruifu

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2021 High quality (R)-(+)-4-Methoxy-α-methylbenzylamine - (S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2 Afatinib Amprenavir Fosamprenavir Intermediate – Ruifu Detail:

Manufacturer Supply; Hot Product; High Purity and Competitive Price
(S)-3-Hydroxytetrahydrofuran CAS: 86087-23-2
Afatinib (formerly BIBW 2992, CAS 439081-18-2) Main Intermediate
Amprenavir (CAS 161814-49-9) and Fosamprenavir (CAS 226700-79-4) Intermediate

Chemical Name	(S)-3-Hydroxytetrahydrofuran
Synonyms	(S)-Tetrahydrofuran-3-ol; (S)-(+)-Tetrahydro-3-furanol
CAS Number	86087-23-2
CAT Number	RF-CC101
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C₄H₈O₂
Molecular Weight	88.11
Boiling Point	80℃
Density	1.103 g/mL at 25℃ (lit.)
Refractive Index	n20/D 1.45(lit.)
Water Solubility	Soluble
Brand	Ruifu Chemical

Item	Specifications
Appearance	Colerless transparent to light yellwow liquid
Purity / Analysis Method	≥99.0% (GC)
Identification	Retention time of the sample should match with the retention time of reference standard
Specific Rotation [α]_D²⁰	+17.5° ± 2.5° (C=2 in MeOH)
Optical Purity	e.e ≥99.0% (GC)
Moisture (K.F)	≤0.50%
(R)-(-)-3-Hydroxytetrahydrofuran	≤0.15%
Any Other Single Impurity	≤0.4%
Total impurities	≤1.0%
Test Standard	Enterprise Standard
Usage	Afatinib, Amprenavir and Amprenavir Phosphate Intermediate

(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2 ROS

Package: Bottle, Fluoride Barrels, 25kg/Barrel, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Afatinib (CAS 439081-18-2) is a potent, covalent/irreversible, and orally bioavailable dual (EGFR/ErbB) receptor tyrosine kinase (RTK) inhibitor with anticancer activity.
Afatinib (CAS 439081-18-2) is a prescription medicine that can be taken orally for the treatment of non-small cell lung cancer (NSCLC) with atypical Epidermal Growth Factor Receptor (EFGR) agents. Afatinib is also prescribed for the treatment of NSCLC with the potential or radiating to other body tissues other than the lungs (metastatic cancer) as detected through an FDA approved examination. Afatinib (CAS 439081-18-2) is a 4-anilinoquinazoline tyrosine kinase suppressor that is available as a dimaleate salt (brand name: Giltrif). The drug is the first FDA-endorsed oncology product by Boehringer Ingelheim.

Amprenavir (CAS 161814-49-9) is a HIV protease inhibitor used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM.
Fosamprenavir (CAS 226700-79-4) (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavi.

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