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2021 Good Quality Aminomalonic Acid Diethyl Ester Hydrochloride - 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate High Purity – Ruifu Featured Image
  • 2021 Good Quality Aminomalonic Acid Diethyl Ester Hydrochloride - 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate High Purity – Ruifu

2021 Good Quality Aminomalonic Acid Diethyl Ester Hydrochloride - 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate High Purity – Ruifu

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2021 Good Quality Aminomalonic Acid Diethyl Ester Hydrochloride - 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate High Purity – Ruifu Detail:

Manufacturer with High Purity and Stable Quality
Supply Irinotecan and Related Intermediates:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4

Chemical Name 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride
CAS Number 143254-82-4
CAT Number RF-PI243
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C11H20Cl2N2O
Molecular Weight 267.2
Brand Ruifu Chemical
Item Specifications
Appearance White or Light Yellow Powder
Assay ≥98.0% (HPLC)
Loss on Drying ≤1.0%
Heavy Metals ≤20ppm
Test Standard Enterprise Standard
Usage Intermediate of Irinotecan Hydrochloride (CAS: 100286-90-6)

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride (CAS: 143254-82-4) with high quality. It is an intermediate typically in the synthesis of  Irinotecan Hydrochloride (CAS: 100286-90-6), a DNA Topoisomerase I Inhibitor.

lrinotecan hydrochloride, a semi-synthetic, water soluble derivative of the potent anticancer agent camptothecin, was launched in Japan for the treatment of lung, ovarian, and cervical cancers. lrinotecan exerts its antitumor activity via inhibition of topoisomerase I, a cellular enzyme that is involved in maintaining the topographic structure of DNA during the process of translation, transcription, and mitosis. lrinotecan undergoes de-esterification in vivo to yield an active metabolite, SN-38, which is 1000-fold more potent than the parent. Although being much less toxic than camptothecin, a significant number of patients in clinical trials exhibited side effects of leukopenia, diarrhea, nauseahromiting, and alopecia. Combination therapy of irinotecan with another widely used anticancer agent, cisplatin, has been reported to be superior to either agent alone. lrinotecan is in clinical trials for gastrointestinal, breast, skin, colorectal, pancreatic cancers, mesothelioma and non-Hodgkin’s lymphoma.

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2021 Good Quality Aminomalonic Acid Diethyl Ester Hydrochloride - 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate High Purity – Ruifu detail pictures

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Our advancement depends on the superior gear ,superb talents and consistently strengthened technology forces for 2021 Good Quality Aminomalonic Acid Diethyl Ester Hydrochloride - 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate High Purity – Ruifu , The product will supply to all over the world, such as: Mecca, Jeddah, Jakarta, We believe in establishing healthy customer relationships and positive interaction for business. Close cooperation with our customers has helped us to create strong supply chains and reap benefits. Our products have gained us widespread acceptance and the satisfaction of our worldwide valued clients.
    • The accounts manager made a detailed introduction about the product, so that we have a comprehensive understanding of the product, and ultimately we decided to cooperate.
    5 Stars By Elsa from Atlanta - 2018.09.23 18:44
    It can be said that this is a best producer we encountered in China in this industry, we feel lucky to work with so excellent manufacturer.
    5 Stars By Ruby from Sao Paulo - 2017.06.25 12:48
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