(R)-3-Amino-1-Butanol CAS 61477-40-5 Purity >99.0% (GC) Dolutegravir Intermediate Factory

Short Description:

Chemical Name: (R)-3-Amino-1-Butanol

Synonyms: (R)-3-Aminobutan-1-ol

CAS: 61477-40-5

Purity: >99.0% (GC)

Appearance: Colorless to Light Yellow Liquid

Intermediate of Dolutegravir (CAS: 1051375-16-6)

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (R)-3-Amino-1-Butanol (CAS: 61477-40-5) with high quality, commercial production. It's an intermediate of Dolutegravir (CAS: 1051375-16-6). We can provide Certificate of Analysis (COA), worldwide delivery, small and bulk quantities available, strong after-sale service. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	(R)-3-Amino-1-Butanol
Synonyms	(R)-3-Aminobutan-1-ol; (3R)-3-Amino-1-Butanol
CAS Number	61477-40-5
CAT Number	RF-CC317
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C4H11NO
Molecular Weight	89.14
Specific Gravity (20/20)	0.95
Refractive Index	1.45
Specific Rotation [α]20/D	-12.0° ~ -10.0° (C=1, EtOH)
Brand	Ruifu Chemical

Specifications:

Appearance	Colorless to Light Yellow Liquid	Light Yellow Liquid
Identification by IR	Conforms to Spectrum of the Standard	Conforms
Identification by GC	Conforms to Retention Time of the Standard	Conforms
Purity by GC (A%)	>99.0%	99.8%
Related Substances	Any Single Impurity: <0.5%	0.09%
Related Substances	Total Impurities: <1.0%	0.28%
S-Isomer (by HPLC A%)	<0.10%	0.02%
Water Content by KF	<0.50%	0.10%
Assay by GC (w/w%)	>99.0%	99.3%

Package & Storage:

Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

FAQ:

Application:

(R)-3-Amino-1-Butanol (CAS: 61477-40-5) can be used as an intermediate in the preparation of compounds having HIV integrase inhibitory activity. (R)-3-Amino-1-Butanol is an intermediate of Dolutegravir (CAS: 1051375-16-6). Dolutegravir (Tivicay) was a new kind of anti-ADIS drug that jointly developed by the British pharmaceutical giant GlaxoSmithKline (GSK) with the Japanese Shionogi Pharmaceutical Company (Shionogi). In August 2013, the US FDA approved dolutegravir (also referred to as S/GSK1349572) for the treatment of HIV-1 infection in adults and children ages 12 years and older in combination with other antiretroviral drugs.