(R)-1-Boc-3-Aminopiperidine CAS 188111-79-7 Purity >99.5% (GC) e.e >99.5% Factory

Short Description:

Chemical Name: (R)-1-Boc-3-Aminopiperidine

Synonyms: (R)-(-)-3-Amino-1-Boc-Piperidine

CAS: 188111-79-7

Purity: >99.5% (GC)

e.e: >99.5%

Appearance: Colorless to Yellow Liquid or Solid

E-Mail: alvin@ruifuchem.com

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Product Detail

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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (R)-1-Boc-3-Aminopiperidine (CAS: 188111-79-7) with high quality, commercial production. Ruifu Chemical offers a wide range of chiral compounds. We can provide Certificate of Analysis (COA), worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	(R)-1-Boc-3-Aminopiperidine
Synonyms	(R)-(-)-3-Amino-1-Boc-Piperidine; (R)-1-Boc-3-Piperidinamine; tert-Butyl (R)-3-Amino-1-Piperidinecarboxylate
CAS Number	188111-79-7
CAT Number	RF-CC348
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C10H20N2O2
Molecular Weight	200.28
Density	1.041±0.060 g/cm3
Refractive Index	1.473
Water Solubility	Immiscible With Water
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	Colorless to Yellow Liquid or Solid
Water Content (K.F)	<0.50%
Purity / Analysis Method	>99.5% (GC)
e.e	>99.5%
Specific Rotation [α]20/D	-30.5° ~ -26.5° (C=1 in DMF)
Infrared Spectrum	Conforms to Structure
NMR	Conforms to Structure
Test Standard	Enterprise Standard
Usage	Chiral Compounds; Pharmaceutical Intermediates

Package & Storage:

Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

FAQ:

Application:

(R)-1-Boc-3-Aminopiperidine (CAS: 188111-79-7) is used as an intermediate in the manufacture of various substances such as pharmaceuticals. (R)-1-Boc-3-Aminopiperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like API (CAS:361442-04-8), Linagliptin (CAS: 668270-12-0), Alogliptin (CAS: 850649-61-5), and other antidiabetic agents. (CAS: 361442-04-8) is a type 2 diabetes drug that can stimulate the pancreas to produce more insulin after the meal. It was reached by the cooperation of AstraZeneca and Bristol-Myers Squibb Company and belongs to DPP-IV inhibitor. It plays the role through inhibiting GLP-l degradation. GLP-I is the hormones naturally produced in the intestine after taking food. (CAS:361442-04-8) can regulate the secretion of insulin and strengthen the utilization of glucose in the peripheral tissues. The single medication of (CAS:361442-04-8) improve blood glucose control and the combined medication of (CAS:361442-04-8) with metformin, sulfonylurea and thiazolidinediones can enhance curative effect. It leads to low risk of hypoglycemia and its adverse reactions are similar to placebo, showing better tolerance.