Hyodeoxycholic Acid (HDCA) CAS 83-49-8 Assay 99.0%~101.0%

Short Description:

Chemical Name: Hyodeoxycholic Acid

Synonyms: HDCA 

CAS: 83-49-8

Assay (Titration): 99.0%~101.0%

Appearance: White or Off-White Powder 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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83-49-8 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Hyodeoxycholic Acid (HDCA) (CAS: 83-49-8) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Hyodeoxycholic Acid, Please contact: alvin@ruifuchem.com

83-49-8 - Chemical Properties:

Chemical Name Hyodeoxycholic Acid 
Synonyms HDCA; α-Hyodeoxycholic Acid; alpha-Hyodeoxycholic Acid; 3α,6α-Dihydroxy-5β-Cholan-24-oic Acid; 3α,6α-Dihydroxy-5β-Cholanoic Acid; 7-Deoxyhyocholicacid; Pig Hyodeoxycholic Acid; (3alpha,5beta,6alpha)-3,6-Dihydroxycholan-24-oic Acid; 3alpha,6alpha-Dihydroxy-5beta-Cholan-24-oic Acid
Stock Status In Stock, Production Capacity 1000kg/Month
CAS Number 83-49-8
Molecular Formula C24H40O4
Molecular Weight 392.58 g/mol
Melting Point 196.0~201.0℃(lit.)
Density 1.128g/cm3
Solubility  Easily Soluble in Ethanol, Slightly Soluble in Acetone, Very Slightly Soluble in Ethyl Acetate, and Almost Insoluble in Water
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Brand Ruifu Chemical

83-49-8 - Specifications:

Items Specifications Results
Appearance White or Off-White Powder   White Powder                 
Odor and Taste Odorless and Has a Slightly Bitter Taste Complies
Melting Point 196.0~201.0℃ 197.3℃
Specific Rotation [a]20/D +7.5° to +9.5° (C=2 in Ethanol) +8.2° 
Mesh Size 100% Pass 80 Mesh   Pass 
Loss on Drying ≤1.00% <0.10%
Residue on Ignition  ≤0.20% <0.10%
Heavy Metals (Pb) ≤10ppm <10ppm
Arsenic Salt (As) ≤1.0ppm <1.0ppm
Related Substances (TLC)
Hyocholic Acid  ≤1.00% <1.00%
Chenodeoxycholic Acid ≤0.50% <0.50%
Unknown Impurities ≤0.30% <0.30%
Microbiological Limit Test    
Total Plate Count ≤1000cfu/g Complies
Total Yeasts & Molds ≤100cfu/g Complies
Salmonella Negative Negative
Escherichia Coli Negative Negative
Residue of Pesticide Negative Negative
Assay (Titration) 99.0~101.0% (Dried Substance) 99.2% 
Infrared Spectrum Comfroms to Structure Complies
Solubility in EtOH Colorless to Pale Yellow Clear (50 mg/ml) Pass
Conclusion The product has been tested and complies with the given specifications
Shelf Life 2 Years When Properly Stored


Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Keep away from strong sunlight, heat, moisture. Store away from oxidizing agents. 
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 


Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system


How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

83-49-8 - Risk and Safety:

Hazard Symbols Xn - Harmful
Risk Codes
R36/37/38 - Irritating to eyes, respiratory system and skin.
R40 - Limited evidence of a carcinogenic effect
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S36 - Wear suitable protective clothing.
S22 - Do not breathe dust.
S37 - Wear suitable gloves.
WGK Germany 3
RTECS FZ2050000
HS Code 2918190090

83-49-8 - Application:

Hyodeoxycholic Acid (HDCA) (CAS: 83-49-8) is extracted and processed from pig bile, which is a secondary bile acid. The appearance is white or off-white powder; it is odorless or slightly fishy, and has a slightly bitter taste. This product is easily soluble in ethanol, slightly soluble in acetone, very slightly soluble in ethyl acetate, and almost insoluble in water.
This product is one of the most widely used gallstone medicine raw materials in the world. It can also be used as a feed lick additive. It is also a raw material for the synthesis of Ursodeoxycholic Acid (UDCA) and other steroids, and it is also used for the production of artificial bezoar the main raw materials.
Hyodeoxycholic Acid is a bile acid that is naturally produced in the liver and released into the digestive system to aid in the digestion and absorption of dietary fats. It belongs to a group of bile acids known as ursodeoxycholic acid, which also includes cholic acid and deoxycholic acid. Hyodeoxycholic acid has been found to have various therapeutic effects, including reducing cholesterol levels, improving liver function, and remedy certain liver and gallbladder diseases. It is also used in the production of pharmaceuticals and as a reagent in biochemical research.
Hyodeoxycholic Acid can inhibit the formation of bile acid and dissolve fat, reduce blood cholesterol and triglycerides. It is suitable for type I a or I hyperlipidemia, atherosclerosis, Pertussis, diphtheria, staphylococcus, etc. have a certain antibacterial effect, can also be used as anti-inflammatory drugs, treatment of chronic bronchitis, pediatric viral upper respiratory tract inflammation and so on.
Hyodeoxycholic Acid is the main acid constituent of hog bile, and for this reason it was used industrially as precursor for steroid synthesis before total synthesis became practical. It can lower blood cholesterol, treat and prevent coronary heart disease, hypertension, etc. 

83-49-8 - Usage:

1. Hyodeoxycholic Acid is suitable for type Ia and Ib hyperlipidemia and atherosclerosis. It has a certain antibacterial effect on Bacillus pertussis, Bacillus diphtheria, Staphylococcus aureus, etc. It is also suitable for cholecystitis, cholecystitis, cholelithiasis and other non-obstructive cholestasis. It can speed up the discharge of gallbladder contrast agent from the liver to aid in visualization. It can promote intestinal fat decomposition and absorption of fat-soluble vitamins, and can be used for indigestion caused by liver and gallbladder diseases. It can be used as an anti-inflammatory drug to treat chronic bronchitis and viral respiratory inflammation in children. Occasionally, it can cause gastrointestinal discomfort, mild diarrhea, etc.
2. Used to lower blood cholesterol.
3. One of the raw materials for the treatment of gallstones; the raw material for the synthesis of Ursodeoxycholic Acid (UDCA) and other steroids; the main raw material for the production of artificial bezoar
4. Lower blood lipids, lower blood cholesterol, lower transaminase, etc.
5. Hyodeoxycholic Acid can lower blood cholesterol, treat and prevent coronary heart disease, hypertension, etc.  

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