D-(-)-Pantolactone CAS 599-04-2 Purity >99.0% (GC) Factory

Short Description:

Chemical Name: D-(-)-Pantolactone 

CAS: 599-04-2

Purity: >99.0% (GC) 

Appearance: White Particulate Powder

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of D-(-)-Pantolactone (CAS: 599-04-2) with high quality. Ruifu Chemical supplys a series of chiral building blocks. Ruifu can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase D-(-)-Pantolactone, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name D-(-)-Pantolactone 
Synonyms D-Pantolactone; (R)-(-)-Pantolactone; Pantolactone; (R)-(-)-α-Hydroxy-β,β-Dimethyl-γ-Butyrolactone;  (R)-(-)-β,β-Dimethyl-α-Hydroxy-γ-Butyrolactone; (R)-3-Hydroxy-4,4-Dimethyldihydrofuran-2(3H)-one; Pantoic Acid γ-Lactone; D-(-)-alpha-Hydroxy-beta,beta-Dimethyl-gamma-Butyrolactone; D-(-)-2-Hydroxy-3,3-Dimethyl-γ-Butyrolactone; D-(-)-Pantoyl Lactone
Stock Status In Stock, Mass Production 
CAS Number 599-04-2
Molecular Formula C6H10O3 
Molecular Weight 130.14 g/mol
Melting Point 90.0 to 94.0℃ 
Boiling Point 120.0~122.0℃/15 mm Hg(lit.)
Sensitive Hygroscopic 
Water Solubility  Soluble in Water, Almost Transparency
Storage Temp.  Cool & Dry Place (2~8℃) 
COA & MSDS Available
Category   Chiral Building Blocks  
Brand Ruifu Chemical


Items Inspection Standards Results
Appearance White Particulate Powder Conforms
Purity / Analysis Method  >99.0% (GC)    99.71%
Specific Rotation [α]20/D -49.0° to -53.0° (C=2 in H2O)
Water by Karl Fischer  <0.50% 0.27%
Free Acid <0.50% <0.50% 
Residue on Ignition <0.10% <0.10%   
Heavy Metals (Pb) ≤0.002% <0.002%
Chloride (Cl) ≤0.005% <0.005%
Yeast Mold ≤100cfu/g Conforms
Escherichia Coli  ≤20MPN/100g Conforms
Staphylococcus Aureus Undetected Undetected
Salmonella Undetected Undetected
Mould ≤10MPN/100g Conforms
Infrared Spectrum Consistent with Structure Complies      
1 H NMR Spectrum  Consistent with Structure Complies      
Conclusion The product has been tested & complies with the specifications


Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by FedEx / DHL Express. Provide fast and reliable delivery. 


Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system


How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

599-04-2 - Risk and Safety:

Safety Description S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
WGK Germany 1
HS Code 2932209090


D-(-)-Pantolactone (CAS: 599-04-2) is an important intermediate in the synthesis of pantothenic acid as well as a degradation product of pantothneic acid in the liver. Causes disorientation and hypothermia, and prevents phenamine-induced hyperthermia.
D-(-)-Pantolactone is a chiral auxiliary used in many asymmetric synthesis reactions. It can be used as a chiral starting material to synthesize other chemicals.
Biological activity D-(-)-Pantolactone is a degradation product of pantothenic acid. pantothenic acid is a water-soluble essential vitamin. Use an intermediate of calcium pantothenate. used as pharmaceutical intermediates used in the synthesis of D-calcium pantothenate, D-Panthenol. 

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