2-(3-Ethoxy-4-Ethoxycarbonylphenyl)acetic Acid CAS 99469-99-5 Repaglinide Intermediate Purity >99.0% (HPLC)

Short Description:

Name: 2-(3-Ethoxy-4-Ethoxycarbonylphenyl)acetic Acid

Synonyms: Ethyl 4-Carboxymethyl-2-Ethoxybenzoate  

CAS: 99469-99-5

Purity: >99.0% (HPLC)

Appearance: White to Off-White Crystalline Powder

Intermediate of Repaglinide (CAS: 135062-02-1) 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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99469-99-5 - Description:

Ruifu Chemical is the leading manufacturer of 2-(3-Ethoxy-4-Ethoxycarbonylphenyl)acetic Acid (CAS: 99469-99-5) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Repaglinide Intermediates, Please contact: alvin@ruifuchem.com

Intermediates of Repaglinide:

99469-99-5 - Chemical Properties:

Chemical Name 2-(3-Ethoxy-4-Ethoxycarbonylphenyl)acetic Acid 
Synonyms Ethyl 4-Carboxymethyl-2-Ethoxybenzoate; 4-Carboxymethyl-2-Ethoxybenzoic Acid Ethyl Ester; 3-Ethoxy-4-Ethoxycarbonyl Phenylacetic Acid; 3-Ethoxy-4-(Ethoxycarbonyl)phenylacetic Acid; 3-Ethoxy-4-(Ethoxycarbonyl)benzeneacetic Acid; 2-[(4-Ethoxycarbonyl)-3-Ethoxyphenyl] Acetic Acid; 4-Ethoxycarbonyl-3-Ethoxyphenylacetic Acid
Impurity Repaglinide Related Compound B; Repaglinide EP Impurity B
Stock Status In Stock, Commercial Production  
CAS Number 99469-99-5 
Molecular Formula C13H16O5
Molecular Weight 252.27 g/mol
Melting Point 78.0 to 82.0℃ 
Density 1.191 
Solubility  Soluble in Methanol
COA & MSDS Available
Origin Shanghai, China
Brand Ruifu Chemical

99469-99-5 - Specifications:

Items Specifications  Results
Appearance White to Off-White Crystalline Powder Complies                     
Melting Point  78.0 to 82.0℃ 80.5℃
Water by Karl Fischer  <1.00% 0.21%
Purity / Analysis Method >99.0% (HPLC)  99.57%
Total Impurities <1.00%  0.43%
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications


Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 


Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system


How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

99469-99-5 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes
41 - Risk of serious damage to eyes
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
HS Code 2942000000

99469-99-5 - Application:

2-(3-Ethoxy-4-Ethoxycarbonylphenyl)acetic Acid (CAS: 99469-99-5) is an intermediate / impurity of Repaglinide (CAS: 135062-02-1). Repaglinide was marketed in the US as an orally active hypoglycemic agent in patients with a type Ⅱ diabetes mellitus, to lower blood glucose in synergistic combination with metformin, when hyperglycemia cannot be controlled by diet, exercise or metformin alone. Repaglinide is a nonsulfonylurea insulin secretagogue that was introduced in the United States in 1998 for type 2 diabetes.

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