Tetrabutylammonium Fluoride Solution (TBAF) CAS 429-41-4 (75% in Water)

Tetrabutylammonium Fluoride (TBAF) (CAS: 429-41-4), is a fluoride salt and a tetrabutylammonium salt. It has a role as a phase-transfer catalyst.
Catalyst for etherification of alcohols and phenols with alkyl halides Catalyst for benzylation reactions.
TBAF is a reagent in organic syntheses in addition, condensation, base-catalyzed cyclization reactions, fluorination and desulfonylation reactions and as a deprotecting agent. Typically dried prior to use.
Tetrabutylammonium Fluoride is widely used in the field of organic synthesis and can be used as fluorination reagent, silylation catalyst for alcohols, phase transfer catalyst, etc.
Tetrabutylammonium Fluoride is used as a fluorinating agent and silylation catalyst for alcohols in organic synthesis, and as a basic reagent in alkylation and hydroxylation reactions. Good cationic phase transfer catalyst. Catalysts for acylation, silicification and silicification
Tetrabutylammonium Fluoride is a commonly used organic soluble fluoride salt. It is used as a base, a phase transfer catalyst, and as a fluoride source. In the research field of fluoride sensor development, TBAF is used as an easy to handle and measurable fluoride anion source. The fluoride in TBAF, once dissolved, can be thought of as a free fluoride with little interaction with the ammonium cation. Since TBAF should not absorb light at wavelengths greater than 240nm, it is useful to monitor sensing reactions with visible spectroscopy.
Since the fluorine atom in tetrabutylammonium fluoride is a strong hydrogen bond acceptor, it is very easy to absorb moisture, so the product is usually Tetrabutylammonium fluoride trihydrate or Tetrabutylammonium fluoride tetrahydrofuran solution is sold. When it is heated to 77℃ under vacuum, the compound will decompose into hydrogen fluoride salt. When the sample is dried at 40℃ under high vacuum, it will still get 10-30 mol% water content and 10% difluoride salt.