4-Hydrazinobenzenesulfonamide Hydrochloride CAS 17852-52-7 Celecoxib Intermediate Purity >98.0% (HPLC)

Short Description:

Name: 4-Hydrazinobenzenesulfonamide Hydrochloride

Synonyms: 4-Sulfonamidophenylhydrazine Hydrochloride

CAS: 17852-52-7

Purity: >98.0% (HPLC)

Appearance: Light Yellow to Pale Brown Powder

Intermediate of Celecoxib (CAS: 169590-42-5)

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 4-Hydrazinobenzenesulfonamide Hydrochloride (CAS: 17852-52-7) with high quality, intermediate of Celecoxib (CAS: 169590-42-5). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Celecoxib Intermediates, Please contact: alvin@ruifuchem.com

Intermediates of Celecoxib:

Chemical Properties:

Chemical Name 4-Hydrazinobenzenesulfonamide Hydrochloride 
Synonyms 4-SPH; 4-SAPH.HCl; 4-Hydrazinobenzene-1-Sulfonamide Hydrochloride; 4-Sulfonamidophenylhydrazine Hydrochloride; 4-Sulfonamidephenylhydrazine HCl; (4-Sulfamoylphenyl)hydrazine Hydrochloride
Stock Status In Stock, Commercial Production  
CAS Number 17852-52-7 
Molecular Formula C6H9N3O2S·HCl 
Molecular Weight 223.68 g/mol
Melting Point 210.0~ 213.0℃(lit.)   
Density 1.644 (at 20℃)
Sensitive Hygroscopic 
Water Solubility  Soluble in Water 
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance Light Yellow to Pale Brown Powder  Complies      
Melting Point 210.0~ 213.0℃ 211.2℃
Loss on Drying <1.00% 0.25% 
Ash Content <0.50% 0.11% 
Single Impurity <0.50% Complies      
Total Impurities <2.00% 0.51%
Heavy Metals (Pb) ≤20ppm <10ppm 
Purity / Analysis Method >98.0% (HPLC)  99.49% 
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Celecoxib (CAS: 169590-42-5)

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Hygroscopic. Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Store away from oxidizing agents, water/moisture and bases. Keep away from sunshine; avoid fire.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory AuditFactory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
TransportationBy Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom SynthesisCan provide custom synthesis services to best fit your research needs.
Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

17852-52-7 - Safety Information:

Risk Codes R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Description S36 - Wear suitable protective clothing
S24/25 - Avoid contact with skin and eyes
WGK Germany 3
RTECS DA9380000
HS Code 2935900090
Hazard Note Irritant

17852-52-7 - Application:

4-Hydrazinobenzenesulfonamide Hydrochloride (CAS: 17852-52-7), pharmaceutical intermediate, mainly used in the production of Celecoxib (CAS: 169590-42-5). Celecoxib and Rofecoxib are two specific inhibitors of cyclooxygenase-2 (COX-2) commonly used in clinic at present. They were successfully developed by GD Searle & Pfizer company in the United States and went on sale in 1999, their trade names: Celebrex. Celebrex, this product has significant analgesic and anti-inflammatory effects, and the incidence of upper gastrointestinal ulcers and other complications is the lowest. Celecoxib is a non-steroidal anti-inflammatory drug, which exerts anti-inflammatory and analgesic effects by inhibiting COX-2 to block the synthesis of prostaglandins from arachidonic acid. It is clinically suitable for the treatment of acute and chronic osteoarthritis and rheumatoid arthritis.

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