Cangrelor Intermediate CAS 163706-58-9 Purity >98.5% (HPLC)

Short Description:

Chemical Name: Cangrelor Intermediate

CAS: 163706-58-9

Purity: >98.5% (HPLC)

Appearance: Light Yellow or Yellow Powder

Intermediate of Cangrelor / Cangrelor Tetrasodium

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401


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163706-58-9 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Cangrelor Intermediate (CAS: 163706-58-9) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Cangrelor Intermediates, Please contact:

Intermediates of Cangrelor:

163706-58-9 - Chemical Properties:

Chemical Name Cangrelor Intermediate 
Synonyms Cangrelor Metabolite; Cangrelor Impurity 3; Cangrelor Triol Impurity; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((2-(Methylthio)ethyl)amino)-2-((3,3,3-Trifluoropropyl)thio)-9H-Purin-9-yl)tetrahydrofuran-3,4-Diol; N-​[2-​(Methylthio)​ethyl]​-​2-​[(3,​3,​3-Trifluoropropyl)​thio]​-Adenosine
Stock Status In Stock, Commercial Production  
CAS Number 163706-58-9
Molecular Formula C16H22F3N5O4S2
Molecular Weight 469.50 
Melting Point 179.0~181.0℃ 
Density 1.70±0.10 g/cm3 
COA & MSDS Available
Origin Shanghai, China
Category   Intermediate of Cangrelor / Cangrelor Tetrasodium  
Brand Ruifu Chemical

163706-58-9 - Specifications:

Items Specifications  Results
Appearance Light Yellow or Yellow Powder
Water by Karl Fischer  <0.50% 0.30% 
Purity / Analysis Method >98.5% (HPLC)  98.8% 
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Cangrelor / Cangrelor Tetrasodium  


Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 


Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system


How to Purchase? Please contact Dr. Alvin Huang: or 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

163706-58-9 - Application:

(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((2-(Methylthio)ethyl)amino)-2-((3,3,3-Trifluoropropyl)thio)-9H-Purin-9-yl)tetrahydrofuran-3,4-Diol (CAS: 163706-58-9) is an intermediate of Cangrelor (CAS: 163706-06-7) and Cangrelor Tetrasodium (CAS: 163706-36-3).
On June 22, 2015, the U.S. Food and Drug Administration (FDA) approved Kengreal (Cangrelor), an intravenous antiplatelet drug that prevents harmful blood clot formation in the coronary arteries, the blood vessels that supply blood flow to the heart. It is approved for performing percutaneous coronary intervention (PCI) in adult patients, a procedure used to open a blocked or narrowed coronary artery to improve blood flow to the heart muscle.
Indications and uses
Kengreal (Cangrelor) is a P2Y12 platelet inhibitor and is indicated as an adjunct to percutaneous coronary intervention (PCI) to reduce perioperative myocardial infarction (MI) and repeat coronary revascularization in patients who have not received P2Y12 platelet inhibitors and are not receiving a glycoprotein IIb/IIIa inhibitor, and stent thrombosis (ST) risk.
Cangarello is an intravenous platelet inhibitor with a rapid onset and short half-life compared to the oral platelet inhibitor Clopidogrel. The effect of Cangarello was sustained for 1 hour after intravenous infusion was stopped, and platelet function returned to normal after 1 hour, while the effect of oral antiplatelet drugs lasted for 1 day after withdrawal.  

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