4,5-Dimethoxy-1-Cyanobenzocyclobutane CAS 35202-54-1 Purity >99.0% (HPLC) Ivabradine Hydrochloride Intermediate Factory

Short Description:

Name: 4,5-Dimethoxy-1-Cyanobenzocyclobutane

CAS: 35202-54-1

Purity: >99.0% (HPLC)

Appearance: Off-White to Light Brown Powder

Intermediate of Ivabradine Hydrochloride (CAS: 148849-67-6)

Contact: Dr. Alvin Huang

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Product Detail

Product Tags

Ivabradine Hydrochloride Intermediates:

Ruifu Chemical Supply Ivabradine Hydrochloride Intermediates With High Purity
Ivabradine Hydrochloride CAS 148849-67-6
4,5-Dimethoxy-1-Cyanobenzocyclobutane CAS 35202-54-1
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane Hydrochloride CAS 866783-13-3
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one CAS 73942-87-7
7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one CAS 148870-57-9
3-(3-Chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2(3H)-one CAS 85175-59-3

35202-54-1 - Chemical Properties:

Chemical Name	4,5-Dimethoxy-1-Cyanobenzocyclobutane
Synonyms	4,5-Dimethoxy-1-Benzocyclobutenecarbonitrile; 1-Cyano-4,5-Dimethoxybenzocyclobutene; 3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-Carbonitrile; Ivabradine Hydrochloride Intermediate; Intermediate of IVA 2
CAS Number	35202-54-1
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C11H11NO2
Molecular Weight	189.21
Melting Point	84.0~88.0℃
Density	1.18
Solubility (Soluble in)	Methanol
COA & MSDS	Available
Shelf Life	>2 Years if Stored Properly
Place of Origin	Shanghai, China
Product Categories	Pharmaceutical Intermediates
Brand	Ruifu Chemical

35202-54-1 - Specifications:

Item	Specifications	Results
Appearance	Off-White to Light Brown Powder	Light Brown Powder
Identification	HPLC / UV	Complies
Purity / Analysis Method	>99.0% (HPLC)	99.58%
Melting Point	84.0~88.0℃	86.2℃
Loss on Drying	<0.50% (Dry it at 40℃ till constant weight )	0.05%
Residue on Ignition	<0.10%	0.05%
Related Substances
Individual Impurity	<0.50%	0.29%
Total Impurities	<1.00%	0.42%
Heavy Metals	<10ppm	<10ppm
Conclusion	The product has been tested and complies with the given specifications
Application	Intermediate of Ivabradine Hydrochloride (CAS: 148849-67-6)

35202-54-1 - Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

35202-54-1 - FAQ:

35202-54-1 - Application:

4,5-Dimethoxy-1-Cyanobenzocyclobutane (CAS: 35202-54-1) is an intermediate of Ivabradine Hydrochloride (CAS: 148849-67-6). Ivabradine Hydrochloride has evolved as a specific inhibitor of If current through its contact with f-channels on the intracellular side of the plasma membrane. As a consequence, Ivabradine reduces the speed of diastolic depolarization and decreases heart rate. It has been approved for the treatment of chronic stable angina and provides a viable alternative to patients with a contraindication or intolerance of b-blockers. Evaluation is also underway for the potential treatment of ischemic heart disease.